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In North America, Lyme disease is principally caused by Borrelia burgdorferi sensu stricto, hereafter referred to as “B. burgdorferi.” It is acquired by the bite of an infected Ixodes tick. The most common clinical manifestation is a skin lesion, referred to as “erythema migrans,” which is due to cutaneous infection with B. burgdorferi. Other objective manifestations may involve the nervous sys...

We investigated the appearance and evolution of immunoglobulin M (IgM) and IgG antibodies to Borrelia burgdorferi in 46 patients with culture-proven erythema migrans (EM). All patients received antimicrobial treatment and were prospectively evaluated for up to 1 year. A total of 257 serially collected serum samples were tested by commercial IgG-IgM enzyme-linked immunosorbent assay and separate...

Lyme borreliosis is very important for dermatovenereologists because of its skin manifestations that include erythema chronicum migrans, lymphadenosis benigna cutis, and aerodermatitis chronica atrophicans. In Croatia, the spirochete Borrelia burgodorferi was first isolated in 1991 at University Department of Dermatology and Venereology, Zagreb University Hospital Center. In October 2003, the L...

NOTE. PR, present report; TMP-SMZ, trimethoprim-sulfamethoxazole. in Missouri and other areas where the disease is not endemic needs review. The national Lyme disease surveillance case definition was developed nearly 10 years ago [3], and a great amount of relevant new scientific evidence regarding Lyme disease and southern tick–associated rash illness has accumulated since that time. The findi...

Lyme disease is a complex immune-mediated multi-system disorder that is infectious in origin and inflammatory or "rheumatic" in expression. Through its epidemiologic characteristics, large numbers of a seasonally synchronized patient population are readily available for prospective study. Lyme disease has a known clinical onset ("zero time"), marked by the characteristic expanding skin lesion, ...

Tongue is a most sensitive part of the oral cavity. It is responsible for many functions in the mouth like swallowing, speech, mastication, speaking and breathing. Geographic tongue (Benign migratory glossitis, erythema migrans) is an asymptomatic inflammatory disorder of tongue with controversial etiology. This disease is characterized by erythematous areas showing raised greyish or white circ...

Lyme disease is a tick-borne multisystemic disease with multiple clinical presentations including rheumatological conditions. We present a 12 year old girl complaining of fever, arthralgia and redness in her eyes which was found to be the result of panuveitis. Borrelia antibodies were positive and she received 21-day treatment regimen with Ceftriaxon with resolution of all complaints at the end...

The meningopolyneuritis first described in 1922 by Garin and Bujadoux develops after a tick bite. At the site of the bite in some of the cases, erythema chronicum migrans develops first. Severe pains follow in this area which may spread to other parts of the body. Then peripheral paralysis appears with asymmetrical distribution. The motor cerebral nerves, especially the facial nerve, are also f...

Introduction Lyme disease is caused by Borrelia burgdorferi and is usually transmitted by the bite of an infected tick (Ixodes ricinus). It represents the most common vector-borne illness in Europe. Expanding annular rash (erythema migrans), myalgia, arthralgia, arthritis and neurological symptoms such as facial palsy and lymphocytic meningoradiculitis are typical symptoms. In about 10–15% of p...