Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, 8 Department of Environmental and Occupational Health, School of Public Health, 9 Rutgers University, Piscataway, New Jersey 08854 and 10 Drug Safety Sciences, Johnson & Johnson, Raritan, NJ 08869 11 12 Corresponding author: 13 Dr. Debra L. Laskin 14 Department of Pharmacology and Toxicology 15 Ernest Mario School of Ph...

With the growing number of known 3D protein structures, computing systems, that can predict where two protein molecules interact with each other is becoming of increasing interest. A system is presented, integrating preprocessing like the computation of molecular surfaces, segmentation, and searching for complementarity in the general framework of a pattern analyzing semantic network (ERNEST). ...