Reversible integer mapping is essential for lossless source coding by transformation. A general matrix factorization theory for reversible integer mapping of invertible linear transforms is developed in this paper. Concepts of the integer factor and the elementary reversible matrix (ERM) for integer mapping are introduced, and two forms of ERM—triangular ERM (TERM) and single-row ERM (SERM)—are...

BACKGROUND Ventilator-induced lung injury-(VILI-) induced endothelial permeability is regulated through the Rho-dependent signaling pathway. Ibuprofen inhibits Rho activation in animal models of spinal-cord injury and Alzheimer's disease. The study aims to investigate ibuprofen effects on high tidal volume associated VILI. METHODS Twenty-eight adult male Sprague-Dawley rats were randomized to...

The ezrin, radixin and moesin (ERM) proteins regulate cell membrane architecture in several cellular contexts. Current models propose that ERM activation requires a PtdIns(4,5)P(2)-induced conformational change, followed by phosphorylation of a conserved threonine. However, how these inputs contribute in vivo to orchestrate ERM activation is poorly understood. We addressed this issue by evaluat...

BACKGROUND The epithelial cell rests of Malassez (ERM) are derived from Hertwig's epithelial root sheath (HERS). During development the cells of HERS deposit a variety of molecules on the newly forming root surface. The possibility that ERM retain this potential after root development is completed and secrete bone or cementum-related proteins needs to be investigated. The purpose of this study ...

Notch signaling is crucial for maintaining neural stem cell (NSC) self-renewal and heterogeneity; however, the underlying mechanism is not well understood. In Drosophila, loss of Notch prematurely terminates the self-renewal of larval type II neuroblasts (NBs, the Drosophila NSCs) and transforms type II NBs into type I NBs. Here, we demonstrate that Notch maintains type II NBs by suppressing th...

The aim of this study was to determine both the occurrence and the genetic basis of resistance to erythromycin among 1 235 Staphylococcus spp. isolates obtained between 2000 and 2006 from (a) raw milk and meat (1 704 samples), (b) foodstuffs produced from these (451 samples), and (c) contact surfaces at processing plants and dairy farms (363 samples) in the Czech Republic. Isolates were screene...

The control of self-renewal and differentiation of neural stem and progenitor cells is a crucial issue in stem cell and cancer biology. Drosophila type II neuroblast lineages are prone to developing impaired neuroblast homeostasis if the limited self-renewing potential of intermediate neural progenitors (INPs) is unrestrained. Here, we demonstrate that Drosophila SWI/SNF chromatin remodeling Br...

Ž . One of the expected benefits of membership of the Exchange Rate Mechanism ERM was a reduction in risk which should lead to a lower cost of capital and foster investment and growth. Using the APT, we investigate the behavior of the equity market risk premium for the London Stock Exchange prior to and during sterling’s membership of the ERM. We find that prior to and during the first year of ...