Bacteriophage T4 Lysozyme (T4L) catalyzes the hydrolysis of the peptidoglycan layer of the bacterial cell wall late in the infection cycle. It has long been postulated that equilibrium dynamics enable substrate access to the active site located at the interface between the N- and C-terminal domains. Crystal structures of WT-T4L and point mutants captured a range of conformations that differ by ...

The competition between chemical equilibrium, for example protonation, and physical interactions determines the molecular organization and functionality of biological and synthetic systems. Charge regulation by displacement of acid-base equilibrium induced by changes in the local environment provides a feedback mechanism that controls the balance between electrostatic, van der Waals, steric int...

objectives: the purpose of this study was to compare the accuracy of implant position transfer and surface detail reproduction using two impression techniques and materials. materials and methods: a metal model with two implants and three grooves of 0.25, 0.50 and 0.75 mm in depth on the flat superior surface of a die was fabricated. ten regular-body polyether (pe) and 10 regular-body polyvinyl...