Epidemiological studies of multiple sclerosis have been performed on almost an industrial scale over the past 90 years. Morbidity statistics have been used to generate aetiological hypotheses, to assess local needs for the provision of services and the allocation of resources, and to define the natural history of the disease. Methodological factors have limited the extent to which the many surv...

Although the cause of multiple sclerosis (MS) is unknown, epidemiologic studies support both genetic and environmental components of susceptibility. Reports of clusters, small "epidemics," geographic variation in prevalence, and alteration of MS susceptibility by migration support an environmental factor (or factors). The higher risk for MS in Europeans and in relatives of patients and the exis...

how to cite this article: najafi mr, najafi ma, nasr z. diagnosis and management of multiple sclerosis in children. iran j child neurol. summer 2016; 10(3): 13-23. abstract growing evidence indicates the safety and well toleration of treatment by disease-modifying in children suffering multiple sclerosis (ms). the treatment is not straight forward in a great number of patients, thus patients wi...