The consumption of dietary supplements containing ephedrine and other alkaloids derived from them is quite high all over the world and is mainly used for the purpose of weight loss This consumption has several risks for the general population and for the regulators, since their dissemination is faster than the clinical trials that prove and guarantee its effectiveness and safety of use. We pres...

Background: Hypotension is commonly occurred with Spinal anesthesia. Colloids and Crystalloids are used preoperatively to prevent hypotension. Objective: To examine the effect of fluid (crystalloid vs. colloid) preloading on hemodynamic stability in old patients planned for lower limb orthopedic operations spinal Patients methods: Eighty undergoing surgery under anesthesia were included this wo...

HISTORY OF MESOTHERAPY This review of basic pharmacology using ephedrine as an active medication is provided by Bryan Haycock, MS, CSCS, founder of HSN. As a sympathomimetic, ephedrine acts to stimulate the sympathetic nervous system. It does this by causing presynaptic nerve terminals to release norepinephrine, or what is commonly called noradrenaline (NA), into the synaptic space. It also has...

Contractile responses of vascular smooth muscle strips (rabbit aorta) to angiotensin, vasopressin and serotonin are potentiated by amounts of metanephrine, ephedrine or tyramine that produce no contractions by themselves. Epinephrine and norepinephrine contractions of aortic strips are not potentiated. Phentolamine and bretylium prevent this potentiating effect of metanephrine and ephedrine; th...

Diepvens, Kristel, Klaas R. Westerterp, and Margriet S. Westerterp-Plantenga. Obesity and thermogenesis related to the consumption of caffeine, ephedrine, capsaicin, and green tea. Am J Physiol Regul Integr Comp Physiol 292: R77–R85, 2007. First published July 13, 2006; doi:10.1152/ajpregu.00832.2005.—The global prevalence of obesity has increased considerably in the last decade. Tools for obes...

A traditional Chinese herbal medicine, Kampo medicine, maoto, has been widely used in the treatment of febrile symptoms caused by viral infection. This herbal extract granule for oral use, however, is not well accepted by infants or young children due to its unpleasant taste and odor. Therefore, we prepared Kampo medicine, maoto, suppository and investigated the pharmaceutical and clinical effi...

BACKGROUND AND OBJECTIVES A prospective, randomized study was designed to compare the maternal and neonatal effects of conventional epidural anesthesia and combined spinal epidural anesthesia (CSE) for Cesarean section in severe preeclamptic patients. Additionally, two strategies in the prophylactic management of hypotension in severe preeclamptic patients were evaluated: fluid preloading or pr...

Chloroephedrine is an intermediate and possible contaminant formed when methamphetamine is manufactured using ephedrine or pseudoephedrine as precursors. The purpose of this study was to determine whether this contaminant has biological activity and might contribute to methamphetamine-induced cardiovascular toxicity. In conscious rats, the (-) and (+) isomers of chloroephedrine (0.1 and 1.0 mg/...