introduction: cisplatin is an antineoplastic drug, which is widely used for the treatment of solid tumors. however, its clinical usage is limited because of its side effects such as hepatotoxicity. this study aimed to identify toxic effects of cisplatin on hepatocytes of rats. methods: a total of 45 adult sprague dawley rats weighing 200±30 g were randomly divided into experimental (n=30) and c...

conclusions we found a marked increase in the incidence of non-albicans species (48.2%) among neutropenic patients. only a few strains failed to produce extracellular enzymes. finally, in addition to fluconazole, caspofungin can be considered as the first line treatment against candida species among neutropenic patients. results a total of 110 yeast strains isolated from urine and oral cavities...

background chronic hypoxia causes apoptosis of cardiac myocytes, however, energy production by anaerobic glycolysis protects myocardium against hypoxia injuries. aldolase a is a well-characterised key enzyme of the glycolysis pathway. ghrelin, a 28-amino-acid peptide, synthesizes in the stomach and has protective roles in cardiovascular systems and also affects metabolic pathways. objectives th...

background and objectives: varicella–zoster virus (vzv) is a human herpes virus that usually attacks young children and commonly causes chicken pox (varicella). following primary infection, a lifelong latent infection is established. the virus often reactivates during adulthood or senesces to cause shingles (zoster). little is known regarding the genotypes of varicella in kuwait. the aim of thi...

grape seed proanthocyanidin extract (gspe) has a broad spectrum of biologic properties against oxidative stress. this study aimed to investigate the effects of gspe on biochemical factors and antioxidant enzymes of erythrocyte in diabetic rats. diabetes was induced through single injection of streptozotocin (50 mg.kg-1, i.p). forty male sprague-dawley rats were divided into four groups: group 1...

an experiment was conducted to evaluate the efficacy of exogenous enzymes supplementation (es) on performance, carcass traits and some blood parameters of broilers chickens. one hundred and eighty day old chicks with 40 ± 2 g initial body weight in a completely randomized design with 3 treatments and 4 replications were fed experimental diets included, 1) basal diet no enzymes (control), 2) bas...

even though the use of enzymes as useful analytical reagents when immobilized onto a transducer such as an electrochemical device has been reported in the literature for nearly two decades, the direct, i.e. unmediated electrochemistry of enzymes is, nevertheless, a rather recent development. efforts will be made to introduce the fundamental basis for protein-surface interactions with emphasis o...

GASTRIC STABILITY STUDY OF SUPPLEMENTAL DIGESTIVE ENZYMES In order to meet the cellular demands of adequate nutrients, there must be a good selection of the foods containing the nutrients and also a good digestion/absorption within the gastrointestinal tract. This awareness to ensure good bioavailability of nutrients is gaining more interest. As a result, the administration of supplemental dige...