background and objective: diagnosis of hirschsprung’s disease (hd) as the most common cause of neonatal intestinal obstruction is based on the presence of aganglionosis from seromuscular or full thickness biopsy. due to the complication of full thickness or seromuscular rectal biopsy, mucosal-sub mucosal biopsy is more intended. however, interpretation of these biopsies stained with hematoxylin...

In this paper the performance of cerebrospinal fluid (CSF) protein biomarkers important for monitoring damage of brain astrocytes and neurons for MS is reviewed. We estimated neurofilament, tau and phospho-tau proteins, β-APP, Aβ, S-100B and neuron-specific enolase in CSF of MS patients during relapse. We noted elevation of neurofilament, tau and phospho-tau proteins, S-100B, neuron-specific en...

Serum and plasma gave different electrophoretic patterns when enolase isoenzymes were evaluated by electrophoresis on cellulose acetate. Plasma isoenzyme bands were more intense, and there was an additional one (band P) that was not present in serum. We show that, under the conditions of electrophoresis, some of the residual platelets in the plasma are ruptured, releasing intracellular enolases...

T-Crystallin has been a major component of the cellular lenses of species throughout vertebrate evolution, from lamprey to birds. Immunofluorescence analysis of the embryonic turtle lens, using antiserum to lamprey x-crystallin showed that the protein is expressed throughout embryogenesis and is present at high concentrations in all parts of the lens. Partial peptide sequence for the isolated t...

BackgroundPostoperative neurocognitive decline is a frequent complication in adult patients undergoing major surgery with increased risk for morbidity and mortality. The mechanisms behind cognitive after anaesthesia are not known. We studied the association between CSF blood biomarkers of neuronal injury or brain amyloidosis long-term changes function.MethodsIn orthopaedic (knee hip replacement...

Background & objective: This study aims to assess the effect of cooling helmet during surgery on neuron specific enolase (NSE) and delirium levels following open heart patients with cardiopulmonary bypass (CPB) using a heart-lung machine.
 Methodology: double-blind randomized clinical trial took place from October December 2021 in tertiary care hospital. The research used modified decr...

background: the interaction between serum neuron-specific enolase (nse), biogenic amino-acids and neurobehavioral function with blood lead levels in workers exposed to lead form lead-acid battery manufacturing process was not studied. objective: to evaluate serum nse and biogenic amino-acids (dopamine and serotonin) levels, and neurobehavioral performance among workers exposed to lead from lead...

Abstract The characteristics and roles of tumor associated antigens (TAAs) specific infiltrative T cells (TILs) are not well understood. Alpha-enolase is one TAA oral squamous cell carcinoma (OSCC) pancreatic cancer, highly expressed in many cancer types by analyzing the TCGA database. We detected α-enolase responsive CD8 +T peripheral blood mononuclear (PBMCs) TILs OSCC patients. significantly...

Nature's strategies for evolving catalytic functions can be deciphered from the information contained in the rapidly expanding protein sequence databases. However, the functions of many proteins in the protein sequence and structure databases are either uncertain (too divergent to assign function based on homology) or unknown (no homologs), thereby limiting the utility of the databases. The mec...