Urinary albumin excretion is a predictor for cardiovascular mortality and morbidity. We investigated which parameters determine baseline urinary albumin excretion in nondiabetic subjects, without renal disease. In addition, we evaluated the parameters that predict the albuminuria-lowering efficacy of an angiotensin-converting enzyme inhibitor. In this substudy of the Prevention of Renal and Vas...

A simultaneous pancreas--kidney transplant (SPK) is indicated in patients with type 1 diabetes (T1D) and end-stage renal disease. In patients with type 2 diabetes (T2D) it is not generally indicated,1 because steroid and immunosuppression treatment exacerbates insulin resistance and weight gain. However, in carefully selected patients with T2D who are not obese, SPK results may be similar to th...

INTRODUCTION The Latin American Dialysis and Transplantation Registry (RLDT) includes 20 national affiliates. Data are provided annually by delegates designated by the national affiliate or by the Registry's Coordinating Committee. RESULTS Prevalence of persons on renal replacement therapy (RRT) has increased from 192 patients per million population (pmp) in 1992 to 424 pmp in 2003, a 10% ann...

DURING the past several years the existence of thromboangiitis obliterans as a distinctive disease entity has been seriously questioned. This evidently began with the suggestion by Fisher' that the peripheral manifestations of so-called Buerger's disease might actually represent atherosclerosis of the large arterial trunks with distal thrombosis. A more comprehensive study by Wessler et al.2 ap...

background: vaccination against fatal viral and bacterial diseases is still the best protective way to lower morbidity and mortality rate in end‑stage renal disease (esrd) patients. it has been reported that there is high incidence of low protective levels of igg after vaccination in esrd adult patients. the aim of this study was to evaluate the protective status of vaccination against diphther...

background in the past few decades, chronic kidney disease (ckd) - a disease with progressive decline in renal function - has become an important problem of global public health, not only in developed countries, but also in developing countries with less economic power. objectives in this study, ckd progression to death or end stage renal disease (esrd) in elderly iranian patients was compared ...

Solid organ or stem cell transplantation is a well established procedure in the treatment of endstage diseases (renal disease, chronic liver failure, end-stage pulmonary disease, heart failure). Improved outcome for these patients has allowed us to study some of the complications. One of these is metabolic bone disease, which can hinder their long-term survival and quality of life. In this chap...

BACKGROUND AND OBJECTIVES The effects of different hemoglobin targets when using erythropoiesis-stimulating agents on quality of life are somewhat controversial, and predictors of change in quality of life in endstage renal disease have not been well characterized. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS Five hundred ninety-six incident hemodialysis patients without symptomatic cardiac ...

Much has changed since the launching in the US of the EndStage Renal Disease (ESRD) Program under Medicare on July 1, 1973, a unique entitlement program based solely on the presence of a clinical condition. Dialysis, initially a privilege for a select few, has exploded since then to become a multibillion dollar industry today, with over 600,000 patients on dialysis in the US, and over 1.6 milli...