We have isolated a new class of deletion mutants of phage lambda that extend from the prophage attachment site, att, into the gam and clII genes. In this respect they are similar to certain of the Xpbio transducing phage, but they differ in having a low burst size and in forming minute plaques. Lytically grown stocks of the deletions contain a variable proportion of phage that produce large pla...

Wound infections originate when exogenous or endogenous bacterial pathogens can circumvent the barrier of wound dressing and invade bed. Bacterial colonization causes inflammation, stalls healing process, carries risk dissemination to other tissues. In addition, current antimicrobial dressings fail resolve an infection once it has been established because debris killed bacteria rapidly accumula...

Nisin is an antimicrobial peptide that commonly used as a food preservative and capable of inhibiting the pathogen Listeria monocytogenes. However, nisin ineffective in controlling L. monocytogenes Queso Fresco (QF). To address challenge, this work, we synthetic biology strategies to create series A derivatives by substituting residues 27, 30, 31 32 with positively charged amino acids (H, K R)....