The study of lung emphysema dates back to the beginning of the 17th century. Nevertheless, a number of important questions remain unanswered because a quantitative localized characterization of emphysema requires knowledge of lung structure at the alveolar level in the intact living lung. This information is not available from traditional imaging modalities and pulmonary function tests. Herein,...

Purpose: This study aims to understand the diagnosis and treatment of bronchial foreign bodies (BFBs). Methods and material: We reported a case of BFB that led to severe spontaneous subcutaneous emphysema, and present a general review of the literature on the special clinical features of BFBs. Results: This case characterized by the spontaneous subcutaneous emphysema factor, illustrates that ag...

PURPOSES The aim of the study was to use three-dimensional high-resolution CT scan data sets in inspiration and expiration for the quantitative evaluation of emphysema. Using an advanced dedicated semiautomatic analysis tool, the functional inspiratory/expiratory shifts of emphysema volume and clusters were quantified. The pulmonary function test (PFT) served as the clinical "gold standard." ...

Coronavirus disease 2019 (COVID-19) has spread rapidly around the world and many studies have shown these typical rare atypical findings, such as transient pneumothorax, spontaneous pneumomediastinum (SP), well emphysema subcutaneous during hospitalization. This is case in a 56-year-old woman with COVID-19, who presented hospitalization, of low abundance. As her clinic worsened dyspnea impaired...

process was impaired by inflammation.3,9 These observations were confirmed by means of gas analysis by Lindskog and Van Allen.A Collateral respiration was also demonstrated in relation to experimental segmental emphysema produced by valvular bronchial obstruction. Lobar emphysema followed valvular obstruction of lobar bronchi, but no emphysema resulted from this type of obstruction in the prima...

The incidence of pulmonary emphysema in a series of 50 necropsies on male subjects in Glasgow has been investigated. Emphysema was present in 37 lungs (74%) and found in more than trace amounts in 32 lungs (64%). These results are similar to those previously reported from London, Edinburgh, and Cardiff but emphysema in younger men appears to be more severe in Glasgow than in these other cities....

OBJECTIVE This article describes a patient who developed severe subcutaneous emphysema and a persistent air leak after several attempts at needle thoracostomy for what was thought to be a tension pneumothorax. Subcutaneous emphysema was effectively treated with a topical negative pressure wound therapy dressing applied to a typical subfacial "blowhole" incision. This article aims to describe an...

Subconjunctival emphysema is a condition that must theoretically exist in severe subcutaneous emphysema due to the laxity of the conjunctival tissues. However, this is generally obscured by associated periorbital emphysema and is hidden from view. We present documented evidence of subconjunctival emphysema in the absence of periorbital emphysema. A 53 year old man was admitted with a large righ...

BACKGROUND Numerous studies have demonstrated associations between genetic markers and COPD, but results have been inconsistent. One reason may be heterogeneity in disease definition. Unsupervised learning approaches may assist in understanding disease heterogeneity. METHODS We selected 31 phenotypic variables and 12 SNPs from five candidate genes in 308 subjects in the National Emphysema Tre...

Vitamin A (VA) and its active metabolites play an essential role in lung airway function. Patients with moderate to severe chronic obstructive pulmonary disease (COPD) have a lower serum retinol concentration, and improvement of their 1-second Forced Expiratory Volume (FEV1) is achieved with VA supplementation. In order to test our hypothesis that the VA signaling pathway is compromised in COPD...