amyloid-β (aβ) self-assembly into cross-β amyloidfibrils is implicated in a causative role in alzheimer’s disease pathology.uncertainties persist regarding the mechanisms of amyloid self assembly and the role of metastable prefibrillar aggregates. aβ fibrilsfeature a sheet-turn-sheet motif in the constituent β-strands; as such, turn nucleation has been proposed as a rate-limiting step in the se...

Condition monitoring and protection methods based on the analysis of the machine's current are widely used according to non-invasive characteristics of current transformers. It should be noted that, these sensors are installed by default in the machine control center. On the other hand, condition monitoring based on mathematical methods has been proposed in literature. However, they are model b...

Over the past several decades, obesity has grown into a major global epidemic. In the United States (US), more than two-thirds of adults are now overweight and one-third is obese. In this article, we provide an overview of the state of research on the likely economic impact of the US obesity epidemic at the national level. Research to date has identified at least four major categories of econom...

A large literature suggests that countries with better governance have higher growth rates. We explore whether this is also true at the sub-national level in Indonesia. We exploit a new dataset of firm perceptions of the quality of economic governance in 243 districts across Indonesia to estimate the impact of nine different dimensions of governance on district growth. Surprisingly, we find rel...

In pre-industrial Europe, the pace of economic development and growth varied across territories and over time. Much of this variation was due to the changing impact of government on the economies in question. Government affected the economy principally through its command of violence. We therefore begin by exploring the relationship between violence and economic activity and the relationship be...

The jubilee article presents Academician I. Lukinov's creative and organizational contribution to the development of Ukrainian economic science. author outlines areas scholar's research in Soviet period. significance innovative ideas for overcoming negative trends functioning planned centralized economy is substantiated. scientist’s scientific position revealed as regards justification strategy...

The paper presents a methodology for the quantitative assessment of sustainability applied to the design of chemical plants. Specifically, we focus on the economic and environmental sustainability. The methodology implemented for the economic assessment is the predictive conceptual design (PCD) that uses as indicator the cumulated dynamic economic potential over a long-term horizon. PCD account...