Fabrication, Physicochemical Characterization and Evaluation of In vitro Anticancer Efficacy a Novel pH Sensitive Polymeric Nanoparticles for Efficient Delivery Hydrophobic Drug against Colon CancerManikandan Mahalingam, Kannan Krishnamoorthy

The sub-alpine zones of oceanic islands are unique and dynamic ecosystems with high levels endemism, making them particularly suitable model systems in which to investigate evolutionary biogeographic processes. flora the Canary Islands is restricted Tenerife La Palma. Its origins poorly understood. Echium wildpretii Hook.f. an iconic species subalpine these two islands, distinct subspecies reco...

This study aimed to evaluate the anti-allergic potential of Echium plantagineum L. bee pollen and to characterize its primary metabolites. The activity of E. plantagineum hydromethanolic extract, devoid of alkaloids, was tested against β-hexosaminidase release in rat basophilic leukemic cells (RBL-2H3). Two different stimuli were used: calcium ionophore A23187 and IgE/antigen. Lipoxygenase inhi...

Echium Amoenum (Boraginaceae) is one of the important medicinal herbs in traditional medicine. It has known for its variety effects such as demulcent, anti-inflammatory and analgesic, especially for common cold, anxiolytic and sedative, this plant contains small quantities of pyrrolizidine alkaloids that are toxic and chronic consumption may have adverse effects on the body's organs. in th...

versity through genetic drift, founder effects, and genetic bottlenecks. Such events can reduce a population’s evolutionary potential and increase the risk of extinction. In this chapter, we use plant immigrants as a model system to examine the circumstances in which genetic bottlenecks do (and do not) occur and where in the hierarchical partitioning of genetic diversity such bottlenecks take p...

Changes in vegetation from 1990 to 2000 were examined at 10 high country localities, representing four grassland types: fescue tussock (Festuca novae-zelandiae), snow tussock (Chionochloa rigida), red tussock (C. rubra), and silver tussock (Poa cita). At each locality, three treatments were established: ambient sheep+rabbit grazing, rabbit grazing only, and no grazing. The mutivariate methods o...