نتایج جستجو برای: echinops ilicifolius

تعداد نتایج: 1236  

2015
Sive Finlay Natalie Cooper

It is important to quantify patterns of morphological diversity to enhance our understanding of variation in ecological and evolutionary traits. Here, we present a quantitative analysis of morphological diversity in a family of small mammals, the tenrecs (Afrosoricida, Tenrecidae). Tenrecs are often cited as an example of an exceptionally morphologically diverse group. However, this assumption ...

2014
Petra Jakobs Sebastian Exner Sabine Schürmann Ute Pickhinke Corinna Ortmann Sabine Kupich Philipp Schulz Uwe Hansen

Scube2 enhances proteolytic Shh processing from the surface of producing cells 1 2 Petra Jakobs*, Sebastian Exner*, Sabine Schürmann*, Ute Pickhinke, Shyam 3 Bandari, Corinna Ortmann, Sabine Kupich, Philipp Schulz, Uwe Hansen, Daniela G. 4 Seidler & Kay Grobe 5 6 From the Institute for Physiological Chemistry and Pathobiochemistry, Westfälische 7 Wilhelms Universität Münster, Waldeyerstr. 15, D...

Journal: :Neuron 2013
Nicole H. Wilson Esther T. Stoeckli

Upon reaching their intermediate target, the floorplate, commissural axons acquire responsiveness to repulsive guidance cues, allowing the axons to exit the midline and adopt a contralateral, longitudinal trajectory. The molecular mechanisms that regulate this switch from attraction to repulsion remain poorly defined. Here, we show that the heparan sulfate proteoglycan Glypican1 (GPC1) is requi...

Journal: :Trends in neurosciences 2002
Robert Machold Gord Fishell

Recent work from Agarwala et al. has uncovered exquisite ventral patterning in the mesencephalon. Using electroporation in chicks, they show that ectopic expression of Sonic Hedgehog (Shh) in dorsal mesencephalon can recapitulate this patterning in its entirety. These results are discussed in the context of the purported role of Shh as a morphogen.

Journal: :Mechanisms of Development 1999
Devyn M. Smith Clifford J. Tabin

We have isolated a new chicken gene, cBarx2b, which is related to mBarx2 in sequence, although the expression patterns of the two genes are quite different from one another. The cBarx2b gene is expressed in craniofacial structures, regions of the neural tube, and muscle groups in the limb, neck and cloaca. Perturbation of anterior muscle pattern by application of Sonic Hedgehog protein results ...

Journal: :American journal of physiology. Gastrointestinal and liver physiology 2008
Caroline A Parkin Philip W Ingham

Hedgehog (Hh) proteins are members of a family of secreted signaling factors that orchestrate the development of many organs and tissues including those of the gastrointestinal (GI) tract. The requirement for Hh activity is not limited to early development but underlies the homeostasis of a number of tissues, and abnormal activity of the Hh pathway is associated with several GI malignancies. Un...

Journal: :BioEssays : news and reviews in molecular, cellular and developmental biology 2005
Natasha M M-L Tian David J Price

Some fish exist as eyed, surface-dwelling and eyeless, cave-dwelling forms. The developmental processes that cause eye degeneration in different populations of Astyanax cavefish are similar. Although small optic primordia start to form, apoptosis of lens cells triggers developmental arrest and degeneration of the eyes. Degeneration has been linked to reduced expression of the transcription fact...

Journal: :Cell 1995
Yingzi Yang Lee Niswander

Growth and patterning of the vertebrate limb are controlled by the ridge, posterior mesenchyme, and non-ridge ectoderm. Fibroblast growth factor 4 (FGF4) and Sonic hedgehog (SHH) can mediate signaling from the ridge and posterior mesenchyme, respectively. Here we show that dorsal ectoderm is required together with FGF4 to maintain Shh expression. Removal of dorsal ectoderm results in loss of po...

Journal: :The EMBO Journal 2009
James Briscoe

My grandfather once told me that you should never do anything that might win you a medal. This advice came from his time in the military and although he was a man whose opinion I respected greatly, this was one piece of advice that I never thought would be relevant to me as a scientist. In my defence, it was never my intention or ambition to win a medal: no one could have been more surprised an...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید