Recent developments in medicine have given us a better insight into a group of disorders known as autoimmune diseases. In particular, advances have occurred in our understanding of the Autoimmune Inner Ear Disease (AIED). In this article, the authors review the different postulated theories in the pathogenesis of this disease. The clinical presentation, the available para-clinical diagnostic to...

An 18 year old Chinese girl was admitted with a one week history of fever, headache, constipation and pain in her left ear. She gave a history of re current ear problems during cruldhood. On examination temperature was 39.3 QC with a pulse rate of 1.00 per minute. Pus discharged through a perforation of her left tympanic membrane. The ESR was 100 mm in the first hour, haemoglobin 11.4 Gms/ 100 ...

Hepatic graft rejection is a common complication after liver transplantation (LT), with a maximum incidence within the first weeks. The identification of high-risk patients for early acute rejection (EAR) might be useful for clinicians. A series of 133 liver graft recipients treated with calcineurin inhibitors was retrospectively assessed to identify predisposing factors for EAR and develop a m...

To estimate potential impact of climate change on wheat fusarium ear blight, simulated weather for the A1B climate change scenario was imported into a model for estimating fusarium ear blight in central China. In this work, a logistic weather-based regression model for estimating incidence of wheat fusarium ear blight in central China was developed, using up to 10 years (2001-2010) of disease, ...

The infective capacity of three bacteria commonly encountered during a study of natural middle ear disease in a rat colony has been determined by direct intra-aural injection in young rats. One week after the introduction of B. actinoides 75 per cent of the rats showed a purulent exudate in the injected middle ear cavity and 65 per cent yielded pure cultures of the organism. With hemolytic and ...

Eye and inner ear diseases are the most common sensory impairments that greatly impact quality of life. Zebrafish have been intensively employed to understand the fundamental mechanisms underlying eye and inner ear development. The zebrafish visual and vestibulo-acoustic systems are very similar to these in humans, and although not yet mature, they are functional by 5days post-fertilization (dp...