profound bradycardia during eye surgery is a potentially serious event. in clinical practice oculo-cardiac reflex (ocr) is most often encountered during squint surgery. the objective of this study was to assess the occurrence of ocr and prove the effect of ketamine as an induction drug and anticholinergic premedication (atropine) to prevent ocr. this study comprised 90 patients (aged 4-10 years...

The role of temporary percutaneous endocardial pacing has been examined in a retrospective analysis of all paced patients admitted to one coronary care unit over a 6 year period. The majority of 162 cases (84.6%) were paced for complete heart block complicating acute myocardial infarction. These patients had a higher incidence of previous hypertension, myocardial infarction and diabetes, compar...

Profound bradycardia during eye surgery is a potentially serious event. In clinical practice oculo-cardiac reflex (OCR) is most often encountered during squint surgery. The objective of this study was to assess the occurrence of OCR and prove the effect of ketamine as an induction drug and anticholinergic premedication (atropine) to prevent OCR. This study comprised 90 patients (aged 4-10 years...

Experimental evidence suggests a number of pathologic and electrophysiologic mechanisms that may help initiate ventricular arrhythmias accompanying myocardial ischemia and infarction. Early and late phase events are associated with reentry or an enhancement of focal mechanisms, or both. These can initiate ventricular tachycardia (VT) or ventricular fibrillation (VF), or both. The presence of di...

A young woman who sustained severe head trauma presented to the operating room for emergent surgical intervention. Her electrocardiogram (ECG) exhibited signs of myocardial ischemia, which resolved several days postoperatively. ECG changes suggestive of cardiac pathology can be associated with intracranial pathology, most notably subarachnoid hemorrhage. Delay of operative therapy may have cata...

Gastric pacing has received increasing attention recently. However, few studies have systematically assessed the effect of pacing on gastric dysrhythmias. The aims of this study were to investigate the effect of gastric pacing on gastric dysrhythmia and to explore whether the effect of gastric pacing was mediated via cholinergic nerves. Eight hound dogs implanted with three pairs of serosal ele...

1 Department of Surgery, Vanderbilt University, Nashville, TN, USA 4 2 Department of Physics & Astronomy, Vanderbilt University, Nashville, TN, USA 5 3 Auckland Bioengineering Institute, University of Auckland, New Zealand 6 4 Department of Physics, Lipscomb University, Nashville, TN, USA 7 Division of Vascular Surgery, Vanderbilt University, Nashville, TN, USA 8 6 Department of Surgery, Univer...

OBJECTIVE Loperamide, a non-prescription anti-diarrheal agent, is a peripheral mu-opioid receptor agonist that is excluded from the blood-brain barrier by p-glycoprotein at therapeutic doses. Overdoses of loperamide penetrate the central nervous system (CNS), leading to abuse. We report cardiac conduction abnormalities and dysrhythmias after ingestion of a recreational supra-therapeutic dose of...

Indian red scorpion (Mesobuthus tamulus; MBT) envenomation produces various cardio-respiratory abnormalities including cardiac dysrhythmias. The underlying cell signaling pathways for the cardiac dysrhythmias produced by MBT venom are not known. The present study was therefore conducted to delineate the second messenger signaling pathways involved in MBT venom-induced atrial rhythm changes. The...

The analysis of intracardiac electrogram morphology has been proposed as a complementary method for accurate discrimination between sinus rhythm (SR), supraventricular dysrhythmias, and ventricular dysrhythmias by automatic antitachycardia and cardioverter defibrillator devices. In this study, the performance of a traditional time-domain method for surface electrocardiogram interpretation--Corr...