BACKGROUND & AIMS Colonic strictures complicate inflammatory bowel disease (IBD) and often lead to surgical resection to prevent dysplasia or cancer. We assessed the frequency of dysplasia and cancer among IBD patients undergoing resection of a colorectal stricture. METHODS We analyzed data from the Groupe d'études et thérapeutiques des affections inflammatoires du tube digestif study. This w...

AIMS Topoisomerase IIalpha (TOPOIIalpha) and HER-2/neu are chromosome 17q genes coamplified in various cancers; no data exist for Barrett's oesophagus (BO) and BO adenocarcinoma (ADC). The aim was to investigate gene amplification and protein overexpression of TopoIIalpha and Her-2/neu in non-dysplastic BO, dysplastic BO, Barrett ADC, and chromosome 17 aneusomy. METHODS AND RESULTS Forty-four...

BACKGROUND & AIMS Early detection and treatment of esophageal cancer in Barrett's esophagus may improve patient survival if dysplasia is effectively detected at endoscopy. Typically, four-quadrant pinch biopsy specimens are taken at 2-cm intervals. This study was conducted to determine whether laser-induced fluorescence spectroscopy could be used to detect high-grade dysplasia in patients with ...

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BACKGROUND AND AIMSEndoscopic ablation can eradicate neoplastic Barrett's esophagus (BE) without visible lesions. Cryoballoon (CBA) is an established but relatively newer ablative technique that eliminate BE data on the durability of its treatment effects are lacking. We assessed CBA for BE.METHODSWe performed a single-center cohort study consecutive patients with confirmed low-grade dysplasia,...

Telepathology (TP) is the practice of evaluating pathology cases by the digital transmission of diagnostic slides as either static pictures (static TP) or by a continuous flow of pictures from a robotic microscopy (dynamic TP). The diagnostic efficacy of dynamic TP-based consultation services has not been widely tested. Dysplasia arising in association with chronic ulcerative colitis (CUC) is, ...

A 21-year-old female with a history of right nephrectomy due to trauma presented several years multi-drug resistant hypertension. Her workup included negative autoimmune and vasculitidies panels urine catecholamines. Computed tomography imaging showed an acute hairpin turn her left renal artery. Intra-operatively, the artery demonstrated kinking exhalation. She underwent excision diseased porti...

Dysplasia Epiphysealis Hemimelica (DEH) or Trevor disease is a condition that affects skeletal development characterized by asymmetric abnormal growth in epiphyses cartilage