Mutually inhibitory pacemaker neurons with duty cycle close to 50% operate as a half-center oscillator (anti-phase coordination, i.e., 180 degrees out of phase), even in the presence of weak to modest gap junctional coupling. For electrical coupling strength above a critical value synchronization occurs. But, as shown here with modeling studies, the effects of electrical coupling depend critica...

The European Commission is examining test procedures to ensure that light-duty vehicle emissions are well controlled both in real use and over the legislative test cycle. At the same time, the UN Working Party on Pollution and Energy (GRPE) has developed a Worldwide harmonised Light vehicles Test Procedure (WLTP) that is expected to be used for Type Approval in the EU in the future. To identify...

Purpose Recent progress in retinal laser therapy has centered upon using thermal stress below damage threshold or selective destruction of targeted tissue layers as a stimulus for retinal repair. Temporal modulation, including micropulse, is thought to increase the selectivity of laser treatment, but has not been carefully analyzed. We measure and model the tissue response to continuous-wave (C...

Many applications in wireless sensor networks (WSNs) require energy consumption to be minimized and the data delivered to the sink within a specific delay. A usual solution for reducing energy consumption is duty cycling, in which nodes periodically switch between sleep and active states. By increasing the duty cycle interval, consumed energy can be reduced more. However, a large duty cycle int...

Sonoporation is the ultrasound-induced membrane porosity and has been investigated as a means for intracellular drug delivery and nonviral gene transfection. The dynamic characteristics of sonoporation, such as formation, duration and resealing of the pores in the cell membrane, determine the process of intracellular uptake of molecules or agents of interest that are otherwise obstructed by the...

Duty-cycling has been proposed as an effective mechanism for reducing the energy consumption in wireless sensor networks (WSNs). Asynchronous duty-cycle protocols where the receiver wakes up periodically to check whether there is a transmission and the sender transmits preambles to check if the receiver is awake are widely used in WSNs due to the elimination of complex control mechanisms for to...

This paper investigates the problem of providing network coverage using wireless sensors that operate on low duty cycles (measured by the percentage time a sensor is on or active), i.e., each sensor alternates between active and sleep states to conserve energy with an average sleep period (much) longer than the active period. The dynamic change in topology as a result of such duty-cycling has p...

We study the ensemble velocity of non-processive motor proteins, described with multiple chemical states. In particular, we discuss the velocity as a function of ATP concentration. Even a simple model which neglects the strain dependence of transition rates, reverse transition rates and nonlinearities in the elasticity can show interesting functional dependencies, which deviate significantly fr...

In CMOS multistage clock buffer design, the duty-cycle of clock is liable to be changed when the clock passes through several buffer stages. The pulse-width may be changed due to unbalance of the pand n-OS transistors in the long buffer. This paper describes a delay locked loop with double edge synchronization for use in a clock alignment process. Results of its SPICE simulation, that relate to...