The fabrication of the Al2219 + Si3N4 composites was done by means stir casting process. specimen subjected to microstructural studies. density employed in has been evaluated. Generally, increases as weight percent increases. TGA and DTA were performed at temperatures ranging from 30°C 800°C, with some mass loss noted well thermal stability an AA2219 matrix improved. Under various parameters ap...

Lanthanum phosphate, due to its interesting thermal and mechanical properties is a widely studied material for refractory applications. Sintering processes have already been proposed densify this drive microstructure. Inspired by recent progress on low temperature sintering, we investigate Spark Plasma (LowT-SPS) using hydrated precursor. First, lanthanum phosphate behaviour was TGA/DTA XRD ana...

ABSTRACT. Zinc(II), cadmium(II), tin(II), lead(II) and antimony(III) complexes of creatinine with the composition [M(creat)2Xn].xH2O, (X = Cl or NO3; n 2-6) were prepared. The characterized by analytical spectral methods. analysis FT-IR Raman spectra helps to understand coordination properties ligand determine probable structure complexes. shift in resonances cyclic NH proton 1H NMR when compar...

Internalization and traffic to acidic endosomes of anthrax lethal factor (LF) and protective antigen (PA), bound to the anthrax toxin receptor (ATR), is required for LF translocation into the cytosol, where it can elicit its toxic effects. Dynamin is required for clathrin-mediated endocytosis, and long-term disruption of dynamin function blocks internalization of PA. We have used LFn-DTA, a sur...

A versatile and effectual, three-component one pot (2π + 2π) cycloaddition reaction to the synthesis of substituted azetidines in excellent yields is described. The isonicotinic acid hydrazide (1) as starting materials. Design preparation N-(7-R)-2-oxa-8-azabicyclo[4.2.0]octan-8-yl)isonicotinamide derivatives (4a-h) was carried out by condensation isoniazid with aromatic aldehyde (2a-h), ZnCr2O...

The effect of γ-radiation dosage on the thermal stability cross-linked acrylic polymer "Carbomer-140" (СRB) was investigated. DTA, TGA, and DTG curves show multistage processes occurring in different temperature ranges heating CRB from 25 °C to 500 °C. rates decomposition were determined 40–110 °C, 180–260 260–330 330–500 In combination with results electronic structure calculations, potential ...

In this study, we investigated the effect of an agonistic mAb (DTA-1) against glucocorticoid-induced TNF receptor (GITR) in a murine model of systemic lupus erythematosus-like chronic graft-vs-host disease (cGVHD). A single dose of DTA-1 inhibited the production of anti-DNA IgG1 autoantibody and the development of glomerulonephritis, typical symptoms of cGVHD. DTA-1-treated mice showed clinical...

The protein toxin Pasteurella multocida toxin (PMT) is the causative agent of atrophic rhinitis in pigs, leading to atrophy of the nasal turbinate bones by affecting osteoblasts and osteoclasts. The mechanism of PMT-induced intoxication is a deamidation of α-subunits of heterotrimeric G proteins, including Gαq, Gα13, and Gαi, thereby causing persistent activation of the G proteins. Here we util...