Transcellular propagation of protein aggregates, or proteopathic seeds, may drive the progression of neurodegenerative diseases in a prion-like manner. In tauopathies such as Alzheimer's disease, this model predicts that tau seeds propagate pathology through the brain via cell-cell transfer in neural networks. The critical role of tau seeding activity is untested, however. It is unknown whether...

This study aimed to study the effects of initial cell density and in vitro culture method on the construction of tissue-engineered bone grafts and osteogenic activities. Human mesenchymal stem cells (hMSCs) were seeded onto cubic scaffolds prepared from demineralized bone matrix (DBM) by three methods - static, hydrodynamic, or fibrin hydrogel-assisted seeding. The resulting cell-scaffold const...

Rapeseed as one the most crops is the basic needs of human feeding in order to produce oil. A field experiment was conducted to study the effects of different tillage system, seeding method and rates on yield and its components, as well as, seed oil percentage of rapeseed (Brassica napus L. cv. Hyola-401) during 2011-12 growing season at Rice Research Institute of Iran-Department of Ma...

A 58-year-old female presented with renal colic and was found to have renal transitional cell carcinoma at the time of percutaneous surgery. She developed percutaneous tract seeding that clinically presented as subcutaneous skin nodules. After local treatment with surgical excision and radiation treatment, the patient developed retroperitoneal recurrence 5 years later. Percutaneous tract seedin...

A field study was conducted during kharif, 2021 at College Farm, of Agriculture, Rajendranagar, PJTSAU to evaluate the performance rice varieties under different systems cultivation for Southern Telangana Zone. The treatments consisted three i.e., transplanted with spacing 15 cm x 10 cm, wet direct seeded (Drum seeding) a 30 6-8 and dry 5 row in main plots four RNR 11718, JGL 11118, 24423 15048...

Rangelands are the main source of forage production whose degradation is being accelerated due to improper utilities. Furthermore, re-vegetation of palatable plants like Vicia variabilis is more limited in overgrazed rangelands. The objective of this study was to improve degraded rangelands in Meleh-Kabud (Kermanshah, Iran) through planting Vicia variabilis. The research was conducted at experi...

In Genetic Algorithm (GA), the fitness or quality of individual solutions in the initial population plays a significant part in determining the final optimal solution. The traditional GA with random population seeding technique is simple and proficient however the generated population may contain poor fitness individuals, which take long time to converge to the optimal solution. On the other ha...

Seed availability and leaf litter limit plant establishment in some ecosystems. To evaluate the hypothesis that these factors limit understory plant recruitment in Pinus ponderosa forests, I conducted a seeding and litter removal experiment at six thinned sites in the Fort Valley Experimental Forest, northern Arizona. Experimental seeding of four native species (Penstemon virgatus, Erigeron for...

Seeding heuristics are the most widely used strategies to speed up sequence alignment in bioinformatics. Such strategies are most successful if they are calibrated, so that the speed-versus-accuracy trade-off can be properly tuned. In the widely used case of read mapping, it has been so far impossible to predict the success rate of competing seeding strategies for lack of a theoretical framewor...