AIM Based on a multidisciplinary review of drug use in nursing home residents, this study aimed to identify the most frequent clinically relevant medication problems and to analyse them according to the drugs involved and types of problems. METHODS Cross sectional study auditing drug use by 1354 residents in 23 nursing homes in Bergen, Norway. Data were collected in 1997. A physician/pharmaci...

The elderly are particularly vulnerable to drug-induced morbidity. They may suffer from multiple medical problems leading to long-term drug use. Polypharmacy together with ageing-related changes in pharmacokinetics, pharmacodynamics and homeostatic mechanisms increases the risk of adverse drug reactions. Drug-related problems (adverse drug reactions, therapeutic failure and poisoning) are impor...

Drug-related problems in older people during care transitions have become a major public health problem since they threaten patient safety. The objective of our paper is to investigate the extent and frequency of drug-related problems (discontinuity, adherence, errors, interactions and adverse events) after hospital discharge and the efficacy of interventions intended to reduce them. We include...

OBJECTIVES The objective of this study was to examine the associations between (a) childhood maltreatment (i.e., physical abuse, sexual abuse, and neglect) and subsequent illicit drug use and (b) childhood maltreatment and drug-related problems in young adulthood. METHODS Wave 1 and Wave 3 public-use data from the National Longitudinal Study of Adolescent Health were used. Logistic regression...

Objective To assess if a ward-based clinical pharmacy service resolving drug-related problems improved medication appropriateness at discharge and prevented drug-related hospital readmissions. Method Between March and September 2013, we recruited patients with noncommunicable diseases in a Sri Lankan tertiary-care hospital, for a non-randomized controlled clinical trial. The intervention grou...