نتایج جستجو برای: drug dependence
تعداد نتایج: 736814 فیلتر نتایج به سال:
BACKGROUND Multiple studies have shown that genetic variation in the alpha-2 subunit of the gamma-aminobutyric acid type A (GABA(A)) receptor (GABRA2) is associated with risk for alcohol dependence. Recent reports have suggested that GABRA2 may exert its influence on dependence through factors such as sensitivity to alcohol's intoxicating effects and that GABRA2 may also contribute to a common ...
Combined use of an opioid with a psychostimulant is popular among drug abusers. Such “polydrug use” may increase drug effects or attenuate adverse effects of either drug alone. We proposed that a combination of methamphetamine (meth) and morphine may change physical opioid withdrawal symptoms. Adult male rats were chronically injected with cumulative subcutaneous (s.c.) doses of morphine, meth ...
Nucleus accumbens (Nac) has been considered as a center for the induction of drug dependence. Since a high concentration of the enzyme, nitric oxide synthase (NOS) has been found in the Nac, and this fact that the role of nitric oxide (NO) in acquisition and expression of drug dependence has become clear in recent years, therefore in this study the effects of intraaccumbal injections of L-argin...
Objective: The current study aimed to assess the factor structure, validity, and reliability of the Persian version of Severity of Dependence Scale in alcohol and substance dependent individuals in Iran. In addition, the SDS scores were assessed in terms of a number of demographic factors. Method: SDS was translated to Persian and was subsequently translated back into English. Furthermore, it w...
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