we report three cases of asymptomatic celiac disease identified in children with down syndrome after being screened at around twenty-four months of age.  these cases raise the question as to what age is screening for celiac disease indicated in a child with down syndrome and no symptoms.

chronic lymphocytic leukaemia (cll) is the most common b-cell malignancy in the western world and exists as subtypes with very different clinical courses. myeloid cell leukemia 1 (mcl-1) is one member of bcl-2 family proteins that has been shown to be expressed in various tissues and malignant cells, including cll, where its expression is significantly associated with a failure to achieve compl...

the objective of this study was to diagnose integrative ecological health of an urban stream,which is located in the asian temperate region. the research approach was primarily based on the index ofbiological integrity (ibi) using fish assemblage and a qualitative habitat evaluation index (qhei). and these indexes were compared with long-term conventional chemical dataset during 1996-2005. for ...

Top-down hierarchical clustering can be done in a scalable way. Here we describe a scalable unsupervised clustering algorithm designed for large datasets from a variety of applications. The method constructs a tree of nested clusters top-down, where each cluster in the tree is split according to the leading principal direction. We use a fast principal direction solver to achieve a fast overall ...

The perturbation-based nonlinearity compensation (NLC) method is considered in conjunction with a forward error correction (FEC) code that capable of detecting block errors. FEC decoding performed prior to the NLC, and NLC then only for blocks, could not be decoded correctly. total complexity thus dramatically reduced down 1% some cases w.r.t. standard, hard decision-directed decoding. Negligib...

CONFLICT OF INTEREST none declared. AIM The aim of this research was to ascertain the frequency of three basic cytogenetical types of Down syndrome among Kosova Albanian population and to evaluate the maternal age effect on the frequency of births of children with Down syndrome. METHODS Cytogenetics diagnosis has been made according to the standard method of Moorhead and Seabright. RESULT...

AIM Good-quality sleep is essential for normal learning and memory. Sleep fragmentation and disrupted sleep architecture are commonly observed throughout the lifespan of individuals with Down syndrome, a condition marked by cognitive deficits emerging within the first few months of life. While obstructive sleep apnea syndrome (OSAS) is known to contribute to the loss of sleep quality in Down sy...

BACKGROUND Active fixation leads have provided stable atrial and ventricular pacing; however, long-term follow-up data have not been satisfactory. The purpose of this study was to investigate the long-term reliability of active fixation leads and their electrical characteristic stability. METHODS A total of 1196 pacing leads were implanted in 830 patients consecutively between 2002 and 2013. ...