Dam methylation is an essential factor involved in the virulence of an increasing number of bacterial pathogens including Salmonella enterica. Lack of Dam methylation causes severe attenuation in animal models. It has been proposed that dysregulation of Dam activity is potentially a general strategy for the generation of vaccines against bacterial pathogens. In this review, we focus our attenti...

Multiple regression of genetic evaluations for milk yields of first lactations of 159 Holstein bulls on sire, dam, and maternal grandsire evaluations indicates that the weight for estimated transmitting ability of the dam calculated from the first record of the dam and first records of her herdmates is about as theoretically expected and is markedly superior both to estimated transmitting abili...

In all species so far studied, including man, portacaval shunt causes the same changes in liver morphology, including hepatocyte atrophy, fatty infiltration, deglycogenation, depletion and disorganization of the rough endoplasmic reticulum (RER) and its lining polyribosomes, and variable but less specific damage to other organelles. Many, perhaps all, biosynthetic processes are quickly depresse...

Risk analysis methodologies can be useful tools to help decision-makers in dam safety engineering. One of the inputs needed for Quantitative Risk Analysis is an estimate of the probability of failure of the dam under study. Existing dams have been designed using the factor of safety, which is a concept associated with a certain mathematical model of the physical behavior of the dam. In dam engi...

Age-of-dam adjustment factors are used to preadjust birth and weaning weight data for national beef cattle genetic evaluations. Adjustments are used in order to make the means of the different age-of-dam subclasses similar so that a fair comparison of animals can be performed. A review was made of various research studies that have estimated age-of-dam adjustment factors for birth weight and we...

As a departure from traditional situational perspectives, researchers have given increased attention to the dispositional basis of attitudes. Recently, Hepler and Albarracín (2013) introduced a construct that they called "dispositional attitude" and provided validity evidence for a new scale--the Dispositional Attitude Measure (DAM). Although the DAM was introduced as a "new" approach for asses...

This study was motivated by a concern that Indigenous juvenile offenders were not receiving the benefits of diversionary schemes. Previous research had suggested that Indigenous offenders are diverted at a significantly lower rate than non-Indigenous offenders. This research, however, had not compared rates of diversion after adjusting for offender characteristics and other factors that can be ...

Salmonella isolates that lack or overproduce DNA adenine methylase (Dam) elicited a cross-protective immune response to different Salmonella serovars. The protection afforded by the Salmonella enterica serovar Typhimurium Dam vaccine was greater than that elicited in mice that survived a virulent infection. S. enterica serovar Typhimurium Dam mutant strains exhibited enhanced sensitivity to med...

Eight preparations of soluble amyloid and degraded amyloid (DAM) were compared immunologically. Unlike amyloid fibrils, six of eight preparations of DAM proved to be relatively strong immunogens. Antisera to DAM reacted weakly or not at all with normal human serum or extracts of normal tissues, but were specifically reactive with amyloid fibrils or DAM. Comparative studies of DAM'S from eight d...