Introduction: Glass ionomer cement (GIC) is a dental restorative material that is prone to solubility and degradation. GIC could degrade in presence of water and desiccation due to environmental factors during setting process and eventually might lead to the failure of the restoration. Cigarette smoking brings a complex chemical mixture to oral cavity that can inhibit polymeriz...

INTRODUCTION Nifedipine is a calcium-channel blocking agent that is widely used in the treatment of angina pectoris and systemic hypertension (1). The pharmacokinetics and pharmacodynamics of nifedipine have been investigated in numerous studies (2–4). Clinical experiences gained with oral nifedipine formulations with immediate-release (IR) characteristics clearly show that a steep rise in the ...

We present here a methodology, using holographic interferometry, enabling to measure the pure surface reaction rate constant of the dissolution of a mineral in water, unambiguously free from the influence of mass transport. We use that technique to access to this value for gypsum and we demonstrate that it was never measured before but could be deduced a posteriori from the literature results i...

Objective: To prepare and evaluate lipid based drug delivery systems of Tacrolimus. Methods: Lipid based solid dispersion (SD) and self microemulsifying drug delivery systems (SMEDDS) of Tacrolimus are prepared and evaluated. Firstly, solid dispersions, liquid and solid self microemulsifying drug delivery systems of Tacrolimus were prepared. Prepared formulations were evaluated by dissolution t...