BACKGROUND Molecular typing of methicillin-resistant Staphylococcus aureus (MRSA) is required to study the routes and rates of transmission of this pathogen. Currently available typing techniques are either resource-intensive or have limited discriminatory ability. Multiple-locus variable number tandem repeat analysis (MLVA) may provide an alternative high throughput molecular typing tool with ...

Nowadays, with the rapid development of platform economy, Big Data-based Discriminatory Pricing (BDDP) has become a common phenomenon in which big data and algorithms are applied to excessively seize consumer surplus thus damage rights interests consumers. This work aims explore equilibrium strategies consumers, government, service discuss factors affecting BDDP practice platforms. study constr...

The use of principal components in linear discriminant analysis has been considered by several authors. However, many of the properties of procedures associated with this usage are unknown. Here, using a simulation study, we investigate the power to choose thècorrect' components in the discriminant function. We also include the null case where no component has any discriminatory value.

An evaluation of fluorescent amplified fragment length polymorphism (FAFLP) for typing Neisseria gonorrhoeae using 52 isolates revealed that its discriminatory power approached that of Opa-typing in identifying epidemiologically linked isolates. Automated, accurate sizing of FAFLP amplified fragments permits objective data analysis and storage, making it an attractive method for large surveilla...

A multiple-locus variable-number tandem-repeat analysis (MLVA) using six microsatellite markers was assessed in 127 Candida glabrata isolates. Thirty-seven different genotypes, stable both in vitro and in vivo, were observed. The highest discriminatory power (D = 0.902) was reached by using only four markers. MLVA seems to be relevant for C. glabrata typing.

Discrimination in social sense (e.g., against minorities and disadvantaged groups) is the subject of many laws worldwide, and it has been extensively studied in the social and economic sciences. We tackle the problem of determining, given a dataset of historical decision records, a precise measure of the degree of discrimination suffered by a given group (e.g., an etnic minority) in a given con...

High expression of Inhibitor of apoptosis proteins (IAPs) has been related to colorectal cancer (CRC) progression, resistance to treatment and poor prognosis. TRAIL (TNF-related apoptosis-inducing ligand) through its receptors DR4 (TRAIL-R1) and DR5 (TRAIL-R2) can selectively induce cancer cell apoptosis. The mRNA expression of DR4, DR5, c-IAP1, c-IAP2, XIAP and BIRC5/Survivin genes was examine...