BACKGROUND From 1978 through 1992, the number of patients with tuberculosis in New York City nearly tripled, and the proportion of such patients who had drug-resistant isolates of Mycobacterium tuberculosis more than doubled. METHODS We reviewed, confirmed, and analyzed data obtained during the surveillance of patients with tuberculosis. RESULTS From 1992 through 1994, there was a 21 percen...

BACKGROUND The increase in urban migrants is one of major challenges for tuberculosis control in China. The different characteristics of tuberculosis cases between urban migrants and local residents in China have not been investigated before. METHODOLOGY/PRINCIPAL FINDINGS We performed a retrospective study of all pulmonary tuberculosis patients reported in Songjiang district, Shanghai, to de...

Decision analysis was used to compare three alternative strategies for a 6-mo course of treatment for tuberculosis: directly observed drug therapy (DOT), self-administered fixed-dose combination drug therapy, and self-administered conventional individual drug therapy. Estimates of effectiveness were obtained from the published literature. Estimates of costs were obtained from the literature and...