نتایج جستجو برای: diethyl fumarate def

تعداد نتایج: 14596  

2015
Liang Zheng Simone Cardaci Livnat Jerby Elaine D. MacKenzie Marco Sciacovelli T. Isaac Johnson Edoardo Gaude Ayala King Joshua D. G. Leach RuAngelie Edrada-Ebel Ann Hedley Nicholas A. Morrice Gabriela Kalna Karen Blyth Eytan Ruppin Christian Frezza Eyal Gottlieb

Mutations in the tricarboxylic acid (TCA) cycle enzyme fumarate hydratase (FH) are associated with a highly malignant form of renal cancer. We combined analytical chemistry and metabolic computational modelling to investigate the metabolic implications of FH loss in immortalized and primary mouse kidney cells. Here, we show that the accumulation of fumarate caused by the inactivation of FH lead...

Journal: :Science 1999
T M Iverson C Luna-Chavez G Cecchini D C Rees

The integral membrane protein fumarate reductase catalyzes the final step of anaerobic respiration when fumarate is the terminal electron acceptor. The homologous enzyme succinate dehydrogenase also plays a prominent role in cellular energetics as a member of the Krebs cycle and as complex II of the aerobic respiratory chain. Fumarate reductase consists of four subunits that contain a covalentl...

2011
Tahina Ramananandro

• list(A) is the set of all lists having their elements in A • nil is the empty list • a :: q is the list starting with an element a and continuing with the tail list q • q − is the append (list concatenation) operator: for any list l, we have nil q −l def. l and (a :: q) q −l def. a :: (q q −l). • lterf (l) is the lter operator, recursively de ned as follows: lterf ( ) = and lterf (a :: q) = {...

2004
Grzegorz Bancerek

Let us mention that every non empty relational structure which is trivial and reflexive is also complete. Let T be a relational structure. A type of T is an element of T . Let T be a relational structure. We say that T is Noetherian if and only if: (Def. 1) The internal relation of T is reversely well founded. Let us observe that every non empty relational structure which is trivial is also Noe...

2011
Peter J. C. Moses Clark Kimberling C. Kimberling

The r-Hofstadter triangle and the (1 − r)-Hofstadter triangle are proved perspective, and homogeneous trilinear coordinates are found for the perspector. More generally, given a triangle DEF inscribed in a reference triangle ABC, triangles A′B′C′ and A′′B′′C′′ derived in a certain manner from DEF are perspective to each other and to ABC. Trilinears for the three perspectors, denoted by P ∗, P1,...

Journal: :TPLP 2001
Samir Genaim Jacob M. Howe Michael Codish

This note illustrates theoretical worst-case scenarios for groundness analyses obtained through abstract interpretation over the abstract domains of definite (Def) and positive (Pos) Boolean functions. For Def, an example is given for which any Def-based abstract interpretation for groundness analysis follows a chain which is exponential in the number of argument positions as well as in the num...

Journal: :Discrete Applied Mathematics 2007
Arthur H. Busch Michael Ferrara Nathan Kahl

Let ω0(G) denote the number of odd components of a graph G. The deficiency of G is defined as def(G) = maxX⊆V (G) (ω0(G−X)− |X|), and this equals the number of vertices unmatched by any maximum matching of G. A subset X ⊆ V (G) is called a Tutte set (or barrier set) of G if def(G) = ω0(G − X) − |X|, and an extreme set if def(G − X) = def(G) + |X|. Recently a graph operator, called the Dgraph D(...

Journal: :Environmental Health Perspectives 1982
W J Kozumbo R Kroll R J Rubin

The Ames assay was used to investigate the mutagenicity of several phthalate esters as an approximation of their carcinogenic potential. The ortho diesters, dimethyl phthalate (DMP) and diethyl phthalate (DEP) produced a positive dose-related mutagenic response with Salmonella TA100, but only in the absence of S-9 liver enzymes. Dibutyl, di(2-ethylhexyl), mono(2-ethylhexyl), and butyl benzyl ph...

Journal: :Advanced theory and simulations 2022

In this theoretical work, density functional theory calculations show the effect of small cobalt clusters (Con, n = 1–5) adsorbed on pristine γ-graphyne (γ-GY), and modify N-doped γ-GY monolayers (GYNs-def). Different geometrical configurations are assessed with adsorption energy, charge transfer, states. The system vacancy defects shows a large energy (19.96 eV) for Co5 cluster. This behavior ...

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