An ion chromatographic method was developed which is able to separate five unsubstituted and hydroxy C4 dicarboxylic acids, succinic, malic, tartaric, maleic and fumaric acid, besides the other unsubstituted C2-C5 dicarboxylic acids, oxalic, malonic and glutaric acids, as well as inorganic ions in samples extracted from atmospheric particulate matter. By the application of this method it was fo...

THE usual procedure for the Van Slyke determination of the nitrogen distribution of proteins [Plimmer, 1917] makes no provision for the dicarboxylic acids. A modification was described by Andersen and Roed-Muller [1915] in which the dicarboxylic acids were determined indirectly by the base bound at neutrality to phenolphthalein. With the only two proteins investigated by these authors the metho...

A homologous series of anionic gas-phase clusters of dicarboxylic acids (oxalic acid, malonic acid, succinic acid, glutaric acid, and adipic acid) generated via electrospray ionization (ESI) are investigated using collision-induced dissociation (CID). Sodiated clusters with the composition (Na(+))(2)(n+1)(dicarboxylate(2-)(n+1) for singly charged anionic clusters, where n = 1-4, are observed as...

Dicarboxylic acids are products of the omega-oxidation of monocarboxylic acids. We demonstrate that in rat liver dicarboxylic acids (C5-C16) can be converted into their CoA esters by a dicarboxylyl-CoA synthetase. During this activation ATP, which cannot be replaced by GTP, is converted into AMP and PPi, both acting as feedback inhibitors of the reaction. Thermolabile at 37 degrees C, and optim...

Aliphatic dicarboxylic acids are one of most important components of water-soluble organics in atmospheric aerosol: they can derive from primary emissions from biomass burning and fossil fuel combustion, as well as photochemical oxidation of organic precursors of both anthropogenic and biogenic origin. Therefore, a detailed investigation on concentrations and relative abundance of these compoun...

The research was performed to study the simultaneous detection of a homologous series of α , ω -dicarboxylic acids (C2-C10), oxalic, malonic, succinic, glutaric, adipic, pimelic, suberic, azelaic, and sebacic acids, with capillary electrophoresis using indirect UV detection. Good separation efficiency in 2,6-pyridinedicarboxylic acid as background electrolyte modified with myristyl trimethyl am...

4 Computation of phase and chemical equilibria of water-organic-inorganic mixtures is 5 of significant interest in atmospheric aerosol modeling. A new version of the phase par6 titioning model, named UHAERO, is presented here, which allows one to compute the 7 phase behavior for atmospheric aerosols containing inorganic electrolytes and organic com8 pounds. The computational implementation of t...

In this study, the effect of crocin, a substance found in Crocus sativus L. stigmata on nervous system development and regeneration was investigated. Crocin is a glycosyl ester of the polyene dicarboxylic acid crocetin and is one of the few families of carotenoids found in nature, which are freely soluble in water. In the first experiment, the effect of crocin (30 microM, 60 microM and 120 micr...

The oxidation of acetic acid in the dark by the non-sulfur purple bacterium, Rhodospirillum rubrum, was shown by van Niel (1, 2) to require the presence of either carbon dioxide or trace amounts of the Cb-dicarboxylic acids of the Krebs cycle. These results could readily be interpreted to mean that the oxidation of acetic acid proceeds by way of the Krebs cycle, the presence of COZ being requir...

The direct carboxylation of pyruvate to oxaloacetate (WoodWerkman reaction) was postulated more than 25 years ago as a probable mechanism for the formation of dicarboxylic acids by CO% fixation (1) and a considerable body of evidence on the interrelationship of dicarboxylic acids and CO2 during bacterial growth was interpreted in this light (24). There was no direct evidence for the existence o...