We compared left ventricular (LV) myocardial blood flow and function accompanying severe demand ischemia (rapid atrial pacing in the presence of critical bilateral coronary stenoses) and supply ischemia (complete bilateral coronary occlusion) of the same ischemic regions in 14 pentobarbital-anesthetized dogs. Pacing-induced ischemia resulted in pronounced reductions in average regional epicardi...

BACKGROUND Many cardiovascular risk factors are found in hypertensive patients. The aim of this study was to evaluate the correlation between cardiac abnormalities (ie, diastolic and left ventricular hypertrophy) with other cardiovascular risk factors in postmenopausal women with hypertension. METHODS A total of 200 consecutive postmenopausal women (mean age 47.5+/-4 years) with mild-to-moder...

1. The intra-arterial blood pressure responses to Valsalva’s manoeuvre and postural change were investigated as indices of cardiovascular reflex activity in seventeen Parkinsonian patients on maximally tolerated doses of L( -)-dopa (levodopa) and repeated in nine patients on levodopa with an extracerebral decarboxylase inhibitor, L-alpha methyldopahydrazine. The results were compared with contr...

abstract   background : noise is the most common hazard in the workplace and noise induced hearing loss considered to be the most common occupational disease as well. cigarette smoking, in some studies, has been known to induce hearing loss. the purpose of this study was to evaluate the effect of contemporary exposure to occupational noise and cigarette smoking on hearing.   methods : 478 assem...

introduction: mild cognitive impairment can be considered as an intermediate clinical state between normal cognitive aging and mild dementia. elderly people with this impairment represent an at-risk group for the development of dementia. the aim of this study was to investigate the prevalence of cognitive impairment in community-dwelling older adults by mini-mental state examination (mmse) and ...

Background—Ventricular hypertrophy is a physiological response to pressure overload that, if left untreated, can ultimately result in ventricular dysfunction, including diastolic dysfunction. The aim of this study was to test the hypothesis that frequency-dependent myofilament desensitization, a physiological response of healthy myocardium, is altered in hypertrophied myocardium. Methods and Re...