The contribution of renal needle biopsy (RNB) to make a diagnosis, a treatment selection and a prognostic evaluation of nephropathies is significant. No Moroccan study has evaluated the practice and the contribution of RNB. Our aim was to study RNB indications, to determine the frequency of kidney diseases identified by RNB in our region and make a comparison between clinical and biological dat...

Abstract Background and Aims Early-onset cystic kidney disease is a clinically genetically heterogeneous overlapping group of rare often severe disorders with limited, mostly symptomatic treatment options. We developed utilized inherited polycystic (PKD) models to search for pharmacological agents that can rescue or mitigate the phenotype. Method A high-content screening platform identification...

diabetic foot ulcer (dfu) is considered as one of the main causes of hospitalization in diabetic patients, which can lead to infection, gangrene, amputation, and even death if the necessary care is not provided. based on the recent investigations, one of the most effective tactics to manage diabetic foot ulcer is to form a multidisciplinary team including a general practitioner, a nurse, an edu...

Chronic renal failure is associated almost constantly with a phospho-calcic metabolism disorder, which significant risk factor for increased cardiovascular mortality and morbidity especially in dialysis patients.The objective of our study was to determine the situation concerning mineral bone disease evaluate degree achievement recommended values KDIGO hemodialysis patients center Charles Nicol...

objective(s):diabetic nephropathy is an important long-term complication of diabetes mellitus which appears to be partially mediated by an increase in secretion of transforming growth factor-β (tgf-β). fibromodulin, the small leucine-rich proteoglycan, has been proposed to be the potent tgfβ1 modulator. in this study, the therapeutic effects of recombinant adenoviral vectors expressing fibromod...