Background: COVID-19 is a viral infection that causes pneumonia with dyspnea, cough, and fever. Its outcomes are more severe in patients with diabetes, hypertension, and other disorders than in healthy people. New-onset diabetes and diabetic ketoacidosis (DKA) have been reported as the complications of COVID-19 in several studies. It seems that the prevalence of DKA due to Covid-19 is increasin...

The increasing global prevalence of diabetes is a critical problem for public health. In particular, diabetic retinopathy, a prevalent ocular complication of diabetes mellitus, causes severe vision loss in working population. A better understanding of the pathogenesis and the development of new pharmacologic treatments are needed. This paper describes the relevance between Rho/ROCK pathway and ...

Depression is a common comorbidity of diabetes, undesirably affecting patients’ physical and mental functioning. Psychological interventions are effective treatments for depression in the general population aswell as in patientswith a chronic disease. The aim of this study was to assess the efficacy of individual mindfulnessbased cognitive therapy (MBCT) and individual cognitive behavior therap...

Several medicinal plants are having hypoglycemic effects.[1], The World Health Organization has recommended that the assessment of traditional plant treatments for diabetes mellitus needs further investigation.[2], Several herbal medicines were described for the care of diabetes mellitus in ancient literature of Ayurveda in India. Many of the plants used as diet were reported to have antidiabet...

Recent insights into the neural circuits controlling energy balance and glucose homeostasis have rekindled the hope for development of novel treatments for obesity and diabetes. However, many therapies contribute relatively modest beneficial gains with accompanying side effects, and the mechanisms of action for other interventions remain undefined. This Review summarizes current knowledge linki...

A significant public health issue with serious medical complications and substantial financial implications, diabetes is the quintessential “poster child” among chronic conditions. The complex nature of the condition presents challenges for patients and their physicians – challenges that are not amenable to single solutions or straightforward treatments. Emerging patient-centered, outcomesdrive...

Precision medicine is an increasingly important area of research. Due to the heterogeneity individual characteristics, patients may respond differently treatments. One most goals for precision develop individualized treatment rules (ITRs) involving patients’ characteristics directly. As interesting topic in clinical research, many statistical methods have been developed recent years find optima...

Diabetes mellitus is one of medical conditions that have been extensively investigated. Despite these enormous developments cure for diabetes still remains virtual. The history is backdated to the Egyptian antiquity. As the history became unravelled with regard to the pathophysiological and biochemical bases, medical and surgical treatments and other management strategies, roadmap towards achie...

OBJECTIVE The T helper 17 (Th17) population, a subset of CD4-positive T-cells that secrete interleukin (IL)-17, has been implicated in autoimmune diseases, including multiple sclerosis and lupus. Therapeutic agents that target the Th17 effector molecule IL-17 or directly inhibit the Th17 population (IL-25) have shown promise in animal models of autoimmunity. The role of Th17 cells in type 1 dia...

Diabetes and cancer are common conditions, and their co-diagnosis in the same individual is not infrequent. A link between the two conditions has been postulated for almost 80 years, but only in the past decade has significant epidemiological evidence been amassed to suggest that diabetes and cancer are associated, and the link appears causal. Hyperinsulinaemia, adipocytokines, growth factors a...