Objectives of this study were to determine if concentrations of steroids, insulin-like growth factor-I (IGF-I) and IGF-II in follicular fluid, and numbers of LH and IGF-I receptors change during growth of the dominant follicle. Ovarian follicular development was monitored daily via ultrasound in lactating Holstein cows. Animals were bilaterally ovariectomized when the dominant follicle (DF) was...

BACKGROUND Coronary artery disease (CAD) is associated with an increased prothrombotic tendency and is also linked to unfavourably altered clot microstructure. We have previously described a biomarker of clot microstructure (df) that is unfavourably altered in acute myocardial infarction. The df biomarker assesses whether the blood will form denser or looser microstructures when it clots. In th...

BACKGROUND 21-deoxycortisol (21-DF) is the key intermediate to manufacture pharmaceutical glucocorticoids. Recently, a Japan patent has realized 21-DF production via biotransformation of 17-hydroxyprogesterone (17-OHP) by purified steroid 11β-hydroxylase CYP11B1. Due to the less costs on enzyme isolation, purification and stabilization as well as cofactors supply, whole-cell should be preferent...

Dysgonic fermenter 2 (DF-2) is a fastidious, gram-negative organism well recognized as a cause of fulminant septicemia in patients without spleens or patients with alcoholic cirrhosis. In vitro antibiotic susceptibility testing of eight strains with a Schaedler broth dilution technique revealed DF-2 to be susceptible to all of the antibiotics tested except aztreonam. Previous reports that DF-2 ...

PURPOSE We have previously shown that zebrafish (Danio rerio) embryos can be used as an in vivo model to validate modifiers of the radiation response. Here, we evaluated the radioprotective effect of the nanoparticle DF-1, a fullerene with antioxidant properties, in zebrafish embryos. EXPERIMENTAL DESIGN Zebrafish embryos were exposed to different doses of ionizing radiation ranging from 20 t...

Mounting evidence suggests that the urokinase plasminogen activator (uPA) and its receptor (uPAR) play a central role in tumor progression. The goal of this study was to develop an 89Zr-labeled, antibody-based positron emission tomography (PET) tracer for quantitative imaging of the uPA/uPAR system. An anti-uPA monoclonal antibody (ATN-291) was conjugated with a deferoxamine (Df) derivative and...

The currently best method is the one by Nagai, using df-pn+ to solve brinkmate problems. We have proposed a new threat based and proof number based algorithm called df-pn driven λ-search. We have conducted some preliminary experiments, showing that df-pn driven λ-search seems to be better than Nagai’s method in solving Shogi brinkmate problems. Although more invesigation is requiered, df-pn λ-s...

Depth-first proof-number (df-pn) search is a powerful member of the family of algorithms based on proof and disproof numbers. While df-pn has succeeded in practice, its theoretical properties remain poorly understood. This paper resolves the question of completeness of df-pn: its ability to solve any finite boolean-valued game tree search problem in principle, given unlimited amounts of time an...

Diabetes mellitus as one of the most common metabolic disorders has some complications, one of the main ones is diabetic foot (DF). Appropriate care and education prevents 85% of diabetic foot amputations. An ideal management to prevent and treat diabetic foot necessitates a close collaboration between the health team members and the diabetic patient. Therefore, improving nurses' knowledge a...

Let \(\Omega\subset\mathbf{R}^3\) be a domain and let \(f\colon\Omega\to\mathbf{R}^3\) bi-\(BV\) homeomorphism. Very recently in [16] it was shown that the distributional adjugate of \(Df\) (and thus also \(Df^{-1}\)) is matrix-valued measure. In present paper we show components Adj coincide with \(Df^{-1}(f(U))\) as measures absolutely continuous part equals to pointwise adj \(Df(x)\) a.e. We ...