the pharmacokinetic parameters of domestic and imported ranitidine hydrochloride tablets (ranitidine, formulated and manufactured by kharazmi pharmaceuticals, iran, and zantac ? manufactured by glaxo, uk) were measured in 14 healthy subjects following oral administration of a single 300-mg dose of each brand and compared for bioequivalence evaluation. the pharmaceutical equivalency of both form...

a simple and reproducible hplc method with spectrophotometric detection was developed for determination of rivastigmine in human plasma. liquid-liquid extraction of rivastigmine and donepezil (as internal standard) from plasma samples was performed with 1-butanol/n-hexane (2:98 v/v) in alkaline condition followed by back-extraction into diluted acetic acid. chromatography was carried out using ...

land use may be regarded as one of the most important factors affecting theenvironment with respect to human activities. so far, destroying the rangelands andchanging them into the waste lands and poor rangelands has been proposed as the mostsignificant variations of land use done by human beings. this paper has been conducted toevaluate the variations of vegetation percentage and land uses in ...

background colorectal cancer (crc) is the third most common cancer in iran and its early detection is necessary. this study is based on perception of people in the east of iran toward crc screening.   methods in a cross-sectional study, 1060 randomly selected individuals who referred to razavi hospital of mashhad, iran, between september the 1st, 2012 and february the 28th, 2013 as patients or ...

listeriosis is acknowledged as a major foodborne disease throughout the world caused by listeria monocytogenes. different factors can affect the growth of food borne microbial pathogens. the aim of this study was to investigate the combined effects of different concentrations of bunium persicum essential oil (eo) (0%, 0.08%, 0.16%, 0.24%), three incubation temperatures (35ºc, 25ºc, 4ºc), three ...

in recent years, the needs of the internet are felt in lives of all people.  accordingly, many studies have been done on security in virtual environment. old technics such as firewalls, authentication and encryption could not provide internet security completely; so, intrusion detection system is created as a new solution and a defense wall in cyber environment. many studies were performed on d...

mobile ad-hoc networks (manets) by contrast of other networks have more vulnerability because of having nature properties such as dynamic topology and no infrastructure. therefore, a considerable challenge for these networks, is a method expansion that to be able to specify anomalies with high accuracy at network dynamic topology alternation. in this paper, two methods proposed for dynamic anom...

internet applications spreading and its high usage popularity result insignificant increasing of cyber-attacks. consequently, network security has becomea matter of importance and several methods have been developed for these attacks.for this purpose, intrusion detection systems (ids) are being used to monitor theattacks occurred on computer networks. data mining techniques, machinelearning, ne...

in this paper, a new method is introduced for sperm detection in microscopic images for infertility treatment. in this method, firstly a hypothesis testing function is defined to separate sperms from plasma, non-sperm semen particles and noise. then, some primary candidates are selected for sperms by watershed-based segmentation algorithm. finally, candidates are either confirmed or rejected us...

the major aim of processing satellite images is to prepare topical and effectivemaps. the selection of appropriate classification methods plays an important role. amongvarious methods existing for image classification, artificial neural network method is ofhigh accuracy. in present study, tm images of 1987, and etm+ images of 2000 and 2006were analyzed using artificial fuzzy artmap neural netwo...