Previous studies have shown that spinal neural circuits are modulated by motor skill training. However, the effects of task movement speed on changes in spinal neural circuits have not been clarified. The aim of this research was to investigate whether spinal neural circuits were affected by task movement speed. Thirty-eight healthy subjects participated in this study. In experiment 1, the effe...

In a previous paper we computed the phase response curve (PRC) of a half-center oscillator (HCO), a pair of reciprocally inhibitory model neurons that exhibit alternating rhythms, based on the minimal ionic model. It was showed that the two intrinsic mechanisms of the local HCO, “release” and “escape”, gave rise to two different shapes of PRCs. In this paper we use the theory of weakly coupled ...

The vertebrate diencephalic A11 system provides the sole dopaminergic innervation of hindbrain and spinal cord and has been implicated in modulation of locomotion and sensory processes. However, the exact contributions of sensory stimuli and motor behavior to A11 dopaminergic activity remain unclear. We recorded cellular calcium activity in four anatomically distinct posterior tubercular A11-ty...

Based on the hypothesis that an imbalance in excitatory and inhibitory input is a central mechanism of knee osteoarthritis chronic pain (KOACP), this exploratory study had the following aims: to compare whether the function of the descending inhibitory pain pathway is associated with the state of inhibition in the corticospinal system indexed by the motor-evoked potential (MEP) and the cortical...

the ground reaction curve (grc) is a vital component of the convergence-confinement method, which possesses many applications in the underground space designs. it defines a relation between the tunnel wall deformations and the ground pressure acting on the tunnel walls. generally, grc includes descending and ascending branches. according to many researchers, the descending branch trend for the ...