Objective: To compare the diagnostic performance of direct microscopic techniques and culture media for detecting fungal isolates in hair specimens.Study Design: Cross-sectional study.Place Duration Study: The study was conducted at Department Microbiology, Basic Medical Sciences Institute, Karachi, Pakistan, from January 2021 to June 2021.Materials Methods: A total 207 specimens were collected...

Severe dermatophyte infection is rare in immunocompetent adults. Recently cases have been described in travelers returning from South East Asia (Luchsinger et al., 2015) [1]. These may be sexually transmitted and can have permanent sequelae. We describe the first reported case of Majocchi's granuloma (MG) in an Australian returned traveler and its subsequent transmission via sexual contact. Bot...

The dermatophyte Trichophyton schoenleinii elaborates an extracellular collagenase which is specific for native collagen and gelatin and is separable from an enzyme which is active against Azocoll. The fungal enzyme differs from the bacterial collagenases in its acid pH and small molecular weight. In addition, the fungal enzyme is irreversibly inhibited by ethylenediaminetetraacetic acid, where...

Hybridoma cells produced by fusing myeloma cells with spleen cells from mice immunized with a soluble antigen of Microsporum canis yielded 30 antibody-producing clones. Six of these clones, propagated as ascites tumors in mice, showed two different types of monoclonal antibodies. The type 1 monoclonal antibody reacted with 17 heterologous and 10 homologous dermatophyte antigens. Type 2 monoclon...

A novel dermatophyte species is described in the Microsporum cookei clade. It differs significantly from known taxa in the two molecular markers analyzed, i.e., ITS and partial β-tubulin (BT2). Morphologically the species was characterized by smooth- or only slightly rough-walled conidia, but isolates rapidly became pleomorphic with sparse, smooth- and thick-walled macroconidia in addition to m...

Dermatophyte infections were established in 6.9% of 640 unselected dermatology outpatients attending two district general hospitals in Cumbria over a six-month period. A clinical diagnosis of ringworm was confirmed in the laboratory in 43.1% of hospital and in 21.8% of a smaller series of general practice patients. No result of similar surveys have been published before., Even in a major stock-...

Sebotropic mites have been implicated in the pathogenesis of several dermatoses in humans. A 46 year old male diabetic patient presented with painful, erythematous, papular, rosacea-like eruptions over bilateral cheeks and a rhinophyma of the nasal tip. The lesions were persistent for two years, with negative slit skin smears and unresponsive to treatment attempts. A skin biopsy revealed demode...

Dermatophytes are Fungi which infect keratinized tissues, that is, skin epidermis, hair and nails. Trichophyton violaceum is an anthropophilic, cosmopolitan dermatophyte. It primarily causes tinea capitis and less commonly tinea corporis and tinea unguium. We present a report of two cases of tinea corporis due to T. violaceum in children. Infections due to T. violaceum are important because of ...