Five percent of menstruating women have severe premenstrual symptoms and impairment of functioning defined as premenstrual dysphoric disorder (PMDD). Clinically significant premenstrual symptoms occur in at least an additional 20% of menstruating women. The diagnosis of PMDD should be confirmed by prospective symptom charting over 2 menstrual cycles to confirm the timing of the symptoms and to ...

OBJECTIVE To compare the efficacy of a new low-dose oral contraceptive pill (OCP) formulation with placebo in reducing symptoms of premenstrual dysphoric disorder. METHODS This multicenter, double-blind, randomized clinical trial consisted of 2 run-in and 3 treatment cycles with daily symptom charting; 450 women with symptoms of premenstrual dysphoric disorder were randomized to either placeb...

The cerebellum constitutes ten percent of brain volume and contains the majority of brain neurons. Although it was historically viewed primarily as processing motoric computations, current evidence supports a more comprehensive role, where cerebro-cerebellar feedback loops also modulate various forms of cognitive and affective processing. Here we present evidence for a role of the cerebellum in...

INTRODUCTION It is estimated that up to 75% of premenopausal women experience at least one premenstrual symptom and 8-20% meet clinical criteria for premenstrual syndrome. Premenstrual syndrome substantially reduces quality of life for many women of reproductive age, with pharmaceutical treatments having limited efficacy and substantial side effects. Physical activity has been recommended as a ...

Background: The global incidence of premenstrual syndrome (PMS) and dysphoric disorder (PMDD) is increasing, with increasing suicide reports. However, the bibliometric analysis research on PMS PMDD rare. We aimed to evaluate scientific output explore their hotspots frontiers from 1945 2018 using a methodology. Methods: Articles between were retrieved Web Science Core Collection (WoSCC). used me...

Introduction: About 90 percent of women experience one of Pre-Menstrual Syndrome (PMS) symptoms. PMS is identified with periodic relapse of a combination of physical, psychological and/or troublesome changes that occur during the luteal phase of menstruation cycle. One of psychological symptoms is depression. These symptoms influence on the quality of women relationships in family, workplace an...

BACKGROUND Despite an abundance of clinical research on premenstrual and menstrual symptoms, few epidemiological data provide estimates of the prevalence, incidence, co-morbidity, stability and correlates of premenstrual dysphoric disorder (PMDD) in the community. AIMS To describe the prevalence, incidence, 12 co-morbidity factors and correlates of threshold and subthreshold PMDD in a communi...