نتایج جستجو برای: dependent thalassemia major
تعداد نتایج: 1273294 فیلتر نتایج به سال:
Dermatoglyphs are cutaneous ridges on the fingers, palms, and soles, formed during early intrauterine life. During this period, and only then, genetic and environmental factors can influence their formation. Beta-thalassemia major is an genetic disease. The aim of the present work was to analyze dermatoglyphs traits in subjects with beta-thalassemia major and their thalassemia carrier parents. ...
Background and Aim: Serum ferritin in patients with thalassemia major is an indicator of iron overload, which is the main cause of damage to various organs of the body in patients with thalassemia major. The aim of this study was to investigate the relationship between serum ferritin level and renal function in thalassemia major patients. Materials and Methods: This descriptive and cross-sectio...
BACKGROUND Due to the tropism of human parvovirus B19 to erythroid progenitor cells, infection in patients with an underlying hemolytic disorder such as beta-thalassemia major leads to suppression of erythrocyte formation, referred to as transient aplasia crisis (TAC), which may be life-threatening. We investigated the prevalence of parvovirus B19 among patients with beta thalassemia major atte...
Platelet and factor VIII (F-VIII) storage and phagocytic functions of the spleen were studied in 15 patients with β-thalassemia major who were not splenectomized and in 7 patients with Hb-S-b-thalassemia. Eight splenectomized patients, 4 patients with b-thalassemia major, and 11 healthy children served as controls. F-VIII elevation following adrenalin was not found to be a sensitive index in th...
introduction: beta thalassemia is the most common inherited bloody disorder, affecting synthesis of the beta globin chain of hemoglobin. the type of β-thalassemia mutation affects on the β-globin chain synthesis that appears as β ° ، β + and β ++ -thalassemia. the presence of xmni polymorphic site at the 5 َ region of the g γ-globin gene affects on the rate of g γ chain synthesis and in some con...
abstract introduction : celiac disease (cd) is an autoimmune disorder triggered by ingestion of gluten in genetically predisposed individuals. this study reports evaluated prevalence of cd in patients with beta-thalassemia major. materials and methods: in this case-control study in a period of 3 years which was performed on 620 children in two groups of beta-thalassemia major patients (n=20...
background: iron-mediated cardiomyopathy is the main complication of thalassemia major (tm) patients. therefore, there is an important clinical need in the early diagnosis and risk stratification of patients. the aim of this study was to evaluate the efficacy of tissue doppler imaging (tdi) to study cardiac iron overload in patients with tm using t2* magnetic resonance (mr) as the gold-standard...
background: hepatitis-c infection is a major problem in chronically transfused patients. we compared interferon-α (inf-α) monotherapy with combination of inf-α and amantadine in the treatment of β-thalassemia major patients who were chronically infected with hcv.materials and methods: forty six thalassemia major patients who were chronically infected with hcv were randomly divided into two grou...
Malaventura C, et al. Deferasirox, deferiprone and desferrioxamine treatment in thalassemia major patients: cardiac iron and function comparison determined by quantitative magnetic resonance imaging. Comparison of effects of oral deferiprone and subcutaneous desfer-rioxamine on myocardial iron concentrations and ventricular function in beta-thalassaemia. Effects of chelation therapy on cardiac ...
Background: The role of phosphate hemostasis in development of thalassemia bone disease has not been extensively studied yet. Due to the lack of sufficient human studies about the changes of serum Fibroblast growth factor-23(FGF23) in patients with beta-thalassemia major as the first step of investigating the role of FGF23 in thalassemia bone disease, the present study aimed to investigate the ...
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