Process mining is the automated acquisition of process models from the event logs of information systems. Although process mining has many useful applications, not all inherent difficulties have been sufficiently solved. A first difficulty is that process mining is often limited to a setting of non-supervised learning since negative information is often not available. Moreover, state transition...

introduction a landslide or landslip is a geological phenomenon which includes a wide range of ground movement, such as rock falls, deep failure of slopes and shallow debris flows, which can occur in offshore, coastal and onshore environments. although the action of gravity is the primary driving force for a landslide to occur, there are other contributing factors affecting the original slope s...

The simsurv R package allows users to simulate survival (i.e., time-to-event) data from standard parametric distributions (exponential, Weibull, and Gompertz), two-component mixture distributions, or a user-defined hazard function. Baseline covariates can be included under proportional hazards assumption. Clustered event times, for example individuals within family, are also easily accommodated...

Event knowledge is organized on the basis of goals that enable the selection of specific event sequences to organize everyday life activities. Although the medial prefrontal cortex represents event knowledge, little is known about its role in mediating event knowledge complexity. We used functional MRI to investigate the patterns of brain activation while healthy volunteers were engaged in the ...

OBJECTIVE We recently reported that after 26 weeks, exenatide once weekly (EQW) resulted in superior A1C reduction, reduced hypoglycemia, and progressive weight loss compared with daily insulin glargine (IG) in patients with type 2 diabetes who were taking metformin alone or with sulfonylurea. This 84-week extension study assessed the long-term safety and efficacy of EQW versus IG. RESEARCH D...

We investigate the possibility of selecting heavy ion collision events with certain features in the initial state (“event engineering”). Anisotropic flow measurements in heavy ion reactions have confirmed the almost ideal fluid dynamical behaviour of the hot and dense quark gluon plasma state. As a consequence, it is intriguing to pursue the idea of selecting collisions with a certain special i...

Event correlation has become one of the most important techniques in today’s network management, and there is a clear trend to extend its use to other application domains as well. Unfortunately, existing event correlation systems are often platform-dependent and heavyweight solutions that have complicated design, being therefore difficult to deploy and maintain, and requiring extensive user tra...

OBJECTIVE Metformin produced weight loss and delayed or prevented diabetes in the Diabetes Prevention Program (DPP). We examined its long-term safety and tolerability along with weight loss, and change in waist circumference during the DPP and its long-term follow-up. RESEARCH DESIGN AND METHODS The randomized double-blind clinical trial of metformin or placebo followed by a 7-8-year open-lab...