This paper investigates the problem of path calcul ation of multiple metric routing. Toda 's Internet routing is based on a single metric path selecting algorithm. Single metric path is a best effort service that can only support path for one requirement. In order to support quality-of-service(QoS) call, path is subjec to multiple constraints on routing metric. In many cases, the path finding p...

We present experimental results on shallow junction formation in germanium by phosphorus ion implantation and standard rapid thermal processing. An attempt is made to improve phosphorus activation by implanting phosphorus at high and low temperature. The focus is on studying the germanium damage and phosphorus activation as a function of implant temperature. Rutherford backscattering spectromet...

Mutants of Escherichia coli K-12 that grow more slowly in media containing low concentrations of K have been isolated. All independent mutants of this type which have been studied carry a mutation in a small region of the bacterial chromosome between the supE and gal loci. The growth rate of the mutants is the same as that of the parental strains in medium containing more than 1 mm K, but is on...

The post mortem redistribution of ten commonly prescribed antipsychotic drugs (APs) was investigated. Femoral blood was collected from 273 cases at admission to mortuary (AD) and at post-mortem (PM). The PM samples were collected at various times up to nine days after admission and the sample pairs analysed using LC-MS/MS. The drugs included in this study were 9OH-risperidone (paliperidone), am...

The complex tri-layered structure of the aortic valve (AV) results in anisotropic quasi-static mechanical behaviour. However, its influence on AV viscoelasticity remains poorly understood. Viscoelasticity may strongly influence AV dynamic mechanical behaviour, making it essential to characterise the time-dependent response for designing successful substitutes. This study attempts to characteris...

The objective of the study was to introduce the availability of bold imaging facility at Aga Khan University Hospital Karachi for the first time in Pakistan and also to review the practical application and advantages of functional magnetic resonance imaging (fMRI) and blood oxygen level dependant (BOLD) Imaging Procedures. The study was conducted at Aga Khan University Hospital, Karachi from Au...

This study examines the impacts of relevant factors on the acceptance of internet and e-business technologies in Atlantic Canada’s SMEs (smalland medium-sized enterprises). A research framework was developed and nine hypotheses formulated to test the relationships. A survey was conducted and a total of 162 valid responses were obtained from business owners, managers, etc. Support was found for ...

The hypoxia-inducible transcription factor (HIF) co-ordinates the response of tumours to low oxygen by stimulating genes involved in metabolism and angiogenesis. HIF pathway activation is associated with decreased progression-free survival and increased mortality; compounds that target this pathway are potential agents for the treatment of a range of solid tumour malignancies. Renal cancers are...

A set of seventy four molecules belonging to the class of thioglitazones were subjected to the QSAR analysis for their antihyperglycemic activity. All the molecules were subjected to energy minimization to get 3D structures, followed by conformational analysis to get the conformation of the molecule associated with the least energy and highest stability. Various physico-chemical parameters were...

We discuss the framework of Transductive Support Vector Machine (TSVM) from the perspective of the regularization strength induced by the unlabeled data. In this framework, SVM and TSVM can be regarded as a learning machine without regularization and one with full regularization from the unlabeled data, respectively. Therefore, to supplement this framework of the regularization strength, it is ...