Background: As a very resistant microorganism in infected root canals, Enterococcus faecalis (E. faecalis) can stubbornly survive lethal challenges and invade dentinal tubules, making it the most persistent pathogen canal treatment. is commonly encountered detected infections. These bacteria possess certain virulence factors, tubules resist nutritional deprivation. Proper irrigation an essentia...

OBJECTIVES Endodontic pathogens can penetrate deep into dentinal tubules and therefore survive the chemo-mechanical disinfection procedures. Bacterial penetration has been mainly studies using sliced infected human teeth which, besides creating artifacts, can hinder the observation of the inner tubules due to the dense and opaque dentin structure. The aim of the present study was to develop a s...

introduction: the aim of this in vitro study was to evaluate the effect of 10% citric acid and 17% ethylenediaminetetraacetic acid (edta) irrigating solutions on the surface morphology of young and old root dentin by determining the number and diameter of dentinal tubules using scanning electron microscopy (sem). methods and materials: fifty healthy human teeth collected from young (≤30 years) ...

Cell surface proteins SspA and SspB in Streptococcus gordonii and SpaP in Streptococcus mutans are members of the antigen I/II family of polypeptides produced by oral streptococci. These proteins are adhesins and mediate species-specific binding of cells to a variety of host and bacterial receptors. Here we show that antigen I/II polypeptides are involved in the attachment of oral streptococci ...

INTRODUCTION The objective of this in vitro study is to evaluate the effective and long-term occlusion of dentinal tubules using a novel calcium lactate phosphate (CLP) based desensitizing agent. METHODS Dentin disks (n = 9) were pre-etched using 1 M lactic acid for 30 s and individually treated with Colgate® Pro-Relief™ paste, CLP paste, and double distilled water (ddH₂O) by a rubber-cupped ...

It is known that fractures are more likely to occur in altered teeth, particularly following restoration or endodontic repair; consequently, it is important to understand the structure of altered forms of dentin, the most abundant tissue in the human tooth, in order to better define the increased propensity for such fractures. Transparent (or sclerotic) dentin, wherein the dentinal tubules beco...

The effect of tubule orientation of dentin on the elastic modulus of resin-infiltrated dentin was evaluated. Rectangular cylindricalshaped dentin specimens with their long axis parallel to and perpendicular to dentinal tubules were prepared from extracted premolars. Twenty-five mineralized specimens of each orientation were evaluated. The remaining specimens were then demineralized. The deminer...

Due, in part, to the unique structure of the tooth, dental pain is initiated via distinct mechanisms. Here we review recent advances in our understanding of inflammatory tooth pain and discuss 3 hypotheses proposed to explain dentinal hypersensitivity: The first hypothesis, supported by functional expression of temperature-sensitive transient receptor potential channels, emphasizes the direct t...

Introduction: Dentin hypersensitivity is a pain arising from exposed dentin, typically in response to clinical, thermal, tactile, evaporative or osmotic stimuli that cannot be explained as arising from any other form of dental pathology. Most authorities agree that Brannstrom’s “Hydrodynamic Theory" of nerve stimulation due to movement of dentinal fluid, best explains dentin hypersensitivity. T...