UNLABELLED As increasing amounts of biomonitoring survey data become available, a new discipline focused on converting such data into estimates of chemical exposures has developed. Reverse dosimetry uses a pharmacokinetic model along with measured biomarker concentrations to determine the plausible exposure concentrations-- a critical step to incorporate ground-truthing experimental data into a...

In internal radionuclide therapy, a growing interest in voxel-level estimates of tissue-absorbed dose has been driven by the desire to report radiobiologic quantities that account for the biologic consequences of both spatial and temporal nonuniformities in these dose estimates. This report presents an overview of 3-dimensional SPECT methods and requirements for internal dosimetry at both regio...

To develop and apply a remote dosimetry protocol with PRESAGE® radiochromic plastic and optical-CT readout in the validation of MRI guided radiation therapy (MRgRT) treatments (MRIdian® by ViewRay®). Through multi-institutional collaboration we performed PRESAGE® dosimetry studies in 4ml cuvettes to investigate dose-response linearity, MRcompatibility, and energy-independence. An open calibrati...

Verification of calculated lung dose in an anthropomorphic phantom is performed using two dosimetry media. Dosimetry is complicated by factors such as variations in density at slice interfaces and appropriate position on CT scanning slice to accommodate these factors. Dose in lung for a 6 MV and 10 MV anterior-posterior field was calculated with a collapsed cone convolution method using an ADAC...

This study analyses the thermally stimulated luminescence (TSL) or thermoluminescence glow curve between 300 and 773 K of germanium-doped silica optical fibre and finds a main glow peak at around 500 K with a characteristic spectral emission centred at 400 nm. Both features are particularly suitable for dosimetry. Thus, an investigation by the TSL technique of some first clinically relevant fea...

A quality assurance method that utilizes 3D dosimetry and facilitates clinical interpretation Oldham Mark; Thomas Andrew; O'Daniel Jennifer; Juang Titania; Ibbott Geoffrey; Adamovics John; Kirkpatrick John P International journal of radiation oncology, biology, physics (2012), 84(2), 540-6. PURPOSE: To demonstrate a new three-dimensional (3D) quality assurance (QA) method that provides comprehe...

Reliable information on the heat distribution inside biological tissues is essential for the planning and optimization of experiments which aim to study the effects of non-ionizing radiation (NIR). In electrodynamics, the finite-difference time-domain (FDTD) technique has become the dominant technique for radiofrequency dosimetry. In order to obtain the electromagnetic field and heat distributi...

Post-implantation dosimetry is an important element of permanent prostate brachytherapy. This process relies on accurate localization of implanted seeds relative to the surrounding organs. Localization is commonly achieved using CT images, which provide suboptimal prostate delineation. On MR images, conversely, prostate visualization is excellent but seed localization is imprecise due to distor...

Patient dosimetry is performed in radiology and interventional radiology to assess whether deterministic injuries may occur and to establish the risk of stochastic effects. A fundamental problem for patient dosimetry is that no single quantity can be used to accurately assess both the risk of stochastic effects and whether deterministic injuries will occur following a specific examination or pr...

Radiation dosimetry by Fricke gel was largely used, generally focused and optimized for radiotherapy applications therefore involving relative high dose levels. Fricke gel dosimetry has several advantages, like dose rate and LET almost independence, 3D mapping, among other. This work presents a novel Fricke gel dosimeter optimized for low dose levels. Several chemical composition were studied v...