نتایج جستجو برای: demyelination multiple sclerosis

تعداد نتایج: 789302  

Journal: :Brain 2008
Ansi Chang Maria C. Smith Xinghua Yin Robert J. Fox Susan M. Staugaitis Bruce D. Trapp

Subcortical white matter in the adult human brain contains a population of interneurons that helps regulate cerebral blood flow. We investigated the fate of these neurons following subcortical white matter demyelination. Immunohistochemistry was used to examine neurons in normal-appearing subcortical white matter and seven acute and 59 chronic demyelinated lesions in brains from nine patients w...

Journal: :European Journal of Nuclear Medicine and Molecular Imaging 2019

Journal: :Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 2011

2014
Renaud A. Du Pasquier Daniel D. Pinschewer Doron Merkler

Multiple sclerosis (MS) is a life-long, potentially debilitating disease of the central nervous system (CNS). MS is considered to be an immune-mediated disease, and the presence of autoreactive peripheral lymphocytes in CNS compartments is believed to be critical in the process of demyelination and tissue damage in MS. Although MS is not currently a curable disease, several disease-modifying th...

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