نتایج جستجو برای: dementia

تعداد نتایج: 52767  

2018
Gerd Wallukat Harald Prüss Johannes Müller Ingolf Schimke

Dementia in general and Alzheimer's disease in particular is increasingly seen in association with autoimmunity being causatively or supportively involved in the pathogenesis. Besides classic autoantibodies (AABs) present in dementia patients, there is the new autoantibody class called functional autoantibodies, which is directed against G-protein coupled receptors (GPCRs; GPCR-AABs) and are se...

2016
Li-Jung Elizabeth Ku Ming-Chyi Pai Pei-Yu Shih Sonia Brucki

OBJECTIVE Given the shortage of cost-of-illness studies in dementia outside of the Western population, the current study estimated the annual cost of dementia in Taiwan and assessed whether different categories of care costs vary by severity using multiple disease-severity measures. METHODS This study included 231 dementia patient-caregiver dyads in a dementia clinic at a national university ...

2017
Alvaro Alonso David S. Knopman Rebecca F. Gottesman Elsayed Z. Soliman Amit J. Shah Wesley T. O'Neal Faye L. Norby Thomas H. Mosley Lin Y. Chen

BACKGROUND Atrial fibrillation (AF) has been associated with faster cognitive decline and increased dementia risk. Factors associated with dementia in patients with AF have been seldom studied. METHODS AND RESULTS We studied 6432 individuals from the ARIC-NCS (Atherosclerosis Risk in Communities Neurocognitive Study). In 2011 to 2013, participants underwent a physical exam, echocardiography, ...

2013
Paul Russell Sube Banerjee Jen Watt Rosalyn Adleman Belinda Agoe Nerida Burnie Alex Carefull Kiran Chandan Dominie Constable Mark Daniels David Davies Sid Deshmukh Martin Huddart Ashrafi Jabin Penelope Jarrett Jenifer King Tamar Koch Sanjoy Kumar Stavroula Lees Sinan Mir Dominic Naidoo Sylvia Nyame Ryuichiro Sasae Tushar Sharma Clare Thormod Krish Vedavanam Anja Wilton Breda Flaherty

OBJECTIVE Improving dementia care is a policy priority nationally and internationally; there is a 'diagnosis gap' with less than half of the cases of dementia ever diagnosed. The English Health Department's Quality and Outcomes Framework (QOF) encourages primary care recognition and recording of dementia. The codes for dementia are complex with the possibility of underidentification through mis...

2017
David Singleton Naaheed Mukadam Gill Livingston Andrew Sommerlad

OBJECTIVES To analyse people with dementia and their family carers' attribution of social changes in dementia and the consequences of these attributions. DESIGN Qualitative study, using a semi-structured interview guide. Individual interviews continued to theoretical saturation. Two researchers independently analysed interview transcripts. SETTING AND PARTICIPANTS People with mild dementia ...

2016
Fu-Chi Yang Te-Yu Lin Hsuan-Ju Chen Jiunn-Tay Lee Chun-Chieh Lin Chia-Hung Kao

PURPOSE The association between primary headaches, including tension-type headache (TTH) as one of the most common primary headache disorders, and dementia remains controversial. In this nationwide, population-based, retrospective, cohort study, we explored the potential association between TTH and dementia and examined sex, age, and comorbidities as risk factors for dementia. METHODS Using t...

Journal: :Brain : a journal of neurology 2015
Tobias Skillbäck Bahman Y Farahmand Christoffer Rosén Niklas Mattsson Katarina Nägga Lena Kilander Dorota Religa Anders Wimo Bengt Winblad Jonathan M Schott Kaj Blennow Maria Eriksdotter Henrik Zetterberg

Progressive cognitive decline in combination with a cerebrospinal fluid biomarker pattern of low levels of amyloid-β1-42 and high levels of total tau and phosphorylated tau is typical of Alzheimer's disease. However, several neurodegenerative disorders may overlap with Alzheimer's disease both in regards to clinical symptoms and neuropathology. In a uniquely large cohort of dementia patients, w...

Journal: :Alzheimer's & Dementia 2015
Christina Jensen-Dahm Christiane Gasse Aske Astrup Preben Bo Mortensen Gunhild Waldemar

BACKGROUND Pain is believed to be undertreated in patients with dementia; however, no larger studies have been conducted. The aim was to investigate prevalent use of opioids in elderly with and without dementia in the entire elderly population of Denmark. METHOD A register-based cross-sectional study in the entire elderly (≥65 years) population in 2010 was conducted. Opioid use among elderly ...

Journal: :Alzheimer's & Dementia 2018
Seyed-Mohammad Fereshtehnejad Sara Garcia-Ptacek Dorota Religa Jacob Holmer Kåre Buhlin Maria Eriksdotter Gunilla Sandborgh-Englund

INTRODUCTION Dementia may be associated with discontinuation of regular dental checkups, which in turn results in poorer oral health. METHODS We investigated the trend of change in dental care utilization and the number of teeth before and after being diagnosed with dementia. Longitudinal cognitive- and dental health-related information were merged using data on 58,037 newly diagnosed individ...

2011
Gemma Webster Deborah I. Fels Gary Gowans Vicki L. Hanson

Dementia is a growing concern worldwide. In Scotland alone 1.32% of the population have dementia and about 40% of these people live in a care home or hospital (Care Commission and Mental Welfare Commission, 2009). Dementia is an umbrella term for a persistent impairment in multiple areas of intellectual function including attention, orientation, memory, judgment, language, motor and spatial ski...

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