The number of phalanges and joints are key features of digit 'identity' and are central to limb functionality and evolutionary adaptation. Prior chick work indicated that digit phalanges and their associated joints arise in a different manner than the more sparsely jointed long bones, and their identity is regulated by differential signalling from adjacent interdigits. Currently, there is no ge...

OBJECTIVE To compare the traditional two injections dorsal digital block with volar block in terms of effectiveness of anaesthesia and pain of initial pinprick. STUDY DESIGN Quasi-experimental. PLACE AND DURATION OF STUDY AVH and casualty operation theatres, Mayo Hospital, KEMU, Lahore, from January to June 2007. METHODOLOGY Thirty patients requiring surgical procedure distal to proximal ...

The Sunlight Omnisense is a portable quantitative ultrasound device that measures speed of sound (SOS) at multiple skeletal sites and therefore has the potential to provide a more complete assessment of an individual's overall fracture risk than single-site measurements such as the calcaneus. To provide a robust normative female database, 545 healthy Caucasian women ages 20-90 were recruited at...

An often overlooked aspect of digit development is the special nature of the terminal phalanx, a specialized structure with characteristics distinct from other phalanges, for example the presence of ectodermal derivatives such as nails and claws. Here, we describe the unique ossification pattern of distal phalanges and characteristic gene expression in the digit tips of chick and duck embryos. ...

Background: Dupuytren's disease is a benign fibroproliferative disorder that causes the fingers to be drawn into the palm via formation of new tissue under the glabrous skin of the hand. This disorder causes functional limitations, but it can be treated through a variety of surgical techniques. As a chronic condition, it tends to recur. Objectives: To assess the benefits and harms of different ...

Novel strategies are urgently required to facilitate regeneration of entire bones lost due to trauma or disease. In this study, we present a novel framework for the regeneration of whole bones by tissue engineering anatomically shaped hypertrophic cartilaginous grafts in vitro that subsequently drive endochondral bone formation in vivo. To realize this, we first fabricated molds from digitized ...

Thanks to the help of one ofmy pupils, a native of Madagascar, I was able to collect the following data concerning his own family (Fig.). Both parents are 'normal' and so are all uncles and aunts. The parents have 11 children, 5 boys and 6 girls. Among the children there are two dizygotic unlikesexed twins. Both twins have a fourth distal phalanx on their middle fingers. The female twin has no ...

Introduction Flexor digitorum superficialis (FDS) is the muscle which responsible from the skill actions of the fingers. It has three heads including humeral, ulnar and radial; generally the humeral and ulnar heads are fused together and called as humeroulnar head. The muscle fibers reach the other fingers except the thumb. Each of the muscle beams divides into two parts at the level of the 1st...

A 39-year-old gentleman presented with a painless finger mass that had increased in size over eight years. There was no history of trauma or injury. He denied having any numbness or tingling in his fingers. No similar masses were present elsewhere. Past medical and family histories were non-contributory. Physical examination revealed a non-tender soft mass on the extensor aspect of the right fi...

Objective: Fractures of metacarpals and phalanges are very common fractures, and there are a lot of treatment modalities. The purpose of the study was to describe the technique of percutaneous fixation of phalangeal fractures using a cannulated compression screw fixation system and its results. Methods: We conducted a prospective clinical study on 43 patients with different types of phalangeal ...