This study was undertaken to assess the biochemical changes induced in chronic schistosomiasis and/or chronic HCV, as well as to pinpoint the most significant parameters which could be used as dependable indices for the differentiation of single and coupled infections with or without liver cirrhosis. The selected patients were allocated into 2 broad groups: GrII (Schistosomiasis) which was subd...

Chronic liver injury of any etiology most commonly results in liver fibrosis and eventually cirrhosis and portal hypertension with the attendant risks of decompensated liver failure, hepatocellular carcinoma (HCC) and death. Several studies have shown that successful treatment or removal of the underlying liver injury can result in regression of liver fibrosis and cirrhosis in some patients [1]...

Patients with end-stage liver disease develop acute decompensation (AD) episodes, which become more frequent and might develop into acute-on-chronic liver failure (ACLF). However, it remains unknown how AD induces acceleration of liver disease. We hypothesized that remodeling of collagen type III plays a role in the acceleration of liver cirrhosis after AD and analyzed its formation (Pro-C3) an...

Background and Aims: Decompensated liver cirrhosis has a poor prognosis, with median overall survival of 2-4 years, which is worse than for many oncological disorders. These patients are highly susceptible to infections due increased systemic inflammation leading kidney failure death. The aim was study the efficacy albumin in reducing episodes decompensation, preventing bacterial infection, dys...

Background: Decompensated cirrhosis (DC) in children is the main indication of liver transplantation (LT). The lack access to and impending clinical complications while awaiting affect morbidity mortality pretransplant patients. Granulocyte colony-stimulating factor (G-CSF) therapy has shown promising results adult decompensated as a potential bridging treatment. Our study aimed identify effect...

BACKGROUNDS Serum hepatitis B surface antigen (HBsAg) levels are associated with fibrosis in patients with chronic hepatitis B (CHB) infection. OBJECTIVES The aim of our study was to evaluate serum HBsAg level as a biomarker for compensated cirrhosis in hepatitis B e antigen (HBeAg) positive CHB patients. PATIENTS AND METHODS Two-hundred and one HBeAg-positive Chinese CHB patients with or w...

Background & AimsThe latest Baveno VII consensus provided guidance for determining patients who have truly recompensated from hepatic decompensation. This study aimed to evaluate patients’ transplant-free survival in three different stages of cirrhosis.MethodsAll with chronic hepatitis B virus (HBV) infection and liver cirrhosis treated oral nucleos(t)ide analogues March 2006 December 2022 were...

Aim Insulin-like growth factor 1 (IGF-1), which is primarily produced in hepatocytes and associated with liver functional reserve, plays a crucial role the pathological condition of cirrhosis. This study aimed to investigate usefulness serum IGF-1 levels for predicting long-term prognosis decompensation development patients Methods We retrospectively evaluated 148 cirrhosis divided them into th...