Shale gas currently provides 20% of domestic supply, is targeted by half of the gas-directed drilling rigs, and represents the large majority of domestic resources. However, modern shale plays, their development strategies and their engineering analysis are young by comparison to those of conventional reservoirs. Uncertainty in shale gas reserves has significant implications at both the micro a...

BACKGROUND/AIMS The present study aimed to clarify whether virological response within 2 weeks after therapy initiation can predict a null response to pegylated interferon α-2b plus ribavirin therapy in patients with high viral load genotype 1b hepatitis C. METHODS The participants consisted of 72 patients with high viral load genotype 1b. The dynamics of viral load within 2 weeks were measur...

We describe an observation of the X-ray luminous SN1978K in NGC 1313 using the ACIS detector on Chandra and an archival Newton EPIC observation. The models that provided good fits to the ASCA SIS and GIS and the ROSAT PSPC spectra no longer do so for the ACIS and EPIC spectra. The best-fit model to the ACIS and EPIC spectra are dual hot plasma models (vmekal); one component is soft (T = 0.61 −0...

We present photometric and spectroscopic observations of the Type IIn supernova SN 2019zrk (also known as ZTF20aacbyec). The shows a $\gtrsim$ 100 day precursor, with slow rise, followed by rapid rise to M $\sim -19.2$ in $r$ $g$ bands. post-peak light-curve decline is well fit an exponential decay timescale 39$ days, but it prominent undulations, amplitude 1$ mag. Both light curve spectra are ...

In frog fast skeletal muscle, we find a decline of twitch, tetanus, and maximum K and caffeine contracture tensions as tonicity of the bathing solution is increased. The decline of tension independent of the method of producing contraction indicates that the major effect of hypertonicity is directly on contractile tension probably because of the increased internal ionic strength. However, there...

We present one of the best sampled early-time light curves of a gamma-ray burst (GRB) at radio wavelengths. Using the Arcminute Mircrokelvin Imager (AMI), we observed GRB 130427A at the central frequency of 15.7 GHz between 0.36 and 59.32 d post-burst. These results yield one of the earliest radio detections of a GRB and demonstrate a clear rise in flux less than one day after the γ -ray trigge...

Introduction: Parathyroid dysfunction leading to symptomatic hypocalcemia is not uncommon following a total thyroidectomy and is often associated with significant patient morbidity and a prolonged hospital stay. The current study aimed at evaluating the comparative predictive role of serum calcium and intact parathyroid hormone (iPTH) for post-thyroidectomy hypocalcemia.   Materials and Methods...

A variation of the relative content of (Fe+Ni) versus Ni may be responsible for the observed scatter of Type Ia Supernovae (SNe Ia) about a mean relation between their intrinsic brightness and the shape of their light curve. Synthetic light curves are computed of parametrised Chandrasekhar-mass explosion models of constant kinetic energy, where the ejecta are divided into an inner NSE zone, com...

BACKGROUND a growing number of older patients undergo cardiac surgery. Some of these patients are at increased risk of post-operative functional decline, potentially leading to reduced quality of life and autonomy, and other negative health outcomes. First step in prevention is to identify patients at risk of functional decline. There are no current published tools available to predict function...

The aim of our study was to evaluate whether blood pressure variability influences the rate of cognitive decline in Alzheimer's disease (AD). Two hundred and forty AD patients were periodically evaluated for a 12-month period. The blood pressure (BP) status of each patient was defined through mean and coefficient of variation for both systolic and diastolic BP. Progression of cognitive decline ...