نتایج جستجو برای: dcs

تعداد نتایج: 9738  

Journal: :The Journal of Microbiology, Biotechnology and Food Sciences 2023

Two-dimensional (2D) cell culture systems are normally used for in vitro experiments. These have some drawbacks which affect results of experiments because cultured cells different morphology and physiological properties comparing to vivo models. Therefore, there current technique develop three-dimensional (3D) closer the environment real tissues. In our study, we polycaprolactone fiber scaffol...

2016
Sudhanshu Agrawal Sreerupa Ganguly Alexander Tran Padmaja Sundaram Anshu Agrawal

Aged subjects display increased susceptibility to mucosal diseases. Retinoic Acid (RA) plays a major role in inducing tolerance in the mucosa. RA acts on Dendritic cells (DCs) to induce mucosal tolerance. Here we compared the response of DCs from aged and young individuals to RA with a view to understand the role of DCs in age-associated increased susceptibility to mucosal diseases. Our investi...

Journal: :Journal of the Construction Division and Management 2021

Many developing countries (DCs) are currently spending on construction projects due to the high demand resulting from rapid urbanization. However, results of these in terms time, cost, and quality do not tend meet expectations stakeholders. Despite relevance visibility this situation many DCs, topic has received little research attention. This study examines combined effect six factors that com...

Journal: :Journal of Transport Geography 2021

Distribution centres are becoming more and relevant for spatial planning, due to their rapidly increasing size number. There is little literature, however, that provides a generalized analysis of the functional attributes distribution centres, none discusses relationships between these attributes. Our aim fill this gap by providing new evidence understand relationship. We make use an extensive ...

Brahami, Mustapha Anwar, Dahane, Mohammed, Maliki, Fouad, Sari, Zaki,

A supply chain is a set of facilities connected together in order to provide products to customers. The supply chain is subject to random failures caused by different factors which cause the unavailability of some sites. Given the current economic context, the management of these unavailabilities is becoming a strategic choice to ensure the desired reliability and availability levels of the dif...

Journal: :Journal of immunology 2004
Kena A Swanson Yan Zheng Kathleen M Heidler Zhen-Du Zhang Tonya J Webb David S Wilkes

Lung dendritic cells (DCs) are difficult to study due to their limited quantities and the complexities required for isolation. Although many procedures have been used to overcome this challenge, the effects of isolation techniques on lung DCs have not been reported. The current study shows that freshly isolated DCs (CD11c+) have limited ability to induce proliferation in allogeneic T cells, and...

Journal: :Cancer research 1996
M E Reeves R E Royal J S Lam S A Rosenberg P Hwu

Dendritic cells (DCs) are potent antigen-presenting cells that can activate quiescent T lymphocytes. When pulsed with tumor-associated antigen (TAA) peptide or protein, murine DCs can provide antitumor immunity. We reasoned that DCs retrovirally transduced with TAA genes might have important advantages over peptide- or protein-pulsed DCs, including long-term TAA presentation in vivo, and presen...

2013
Xiaoping Su Cheng Qian Qian Zhang Jin Hou Yan Gu Yanmei Han Yongjian Chen Minghong Jiang Xuetao Cao

Dendritic cells (DCs) are critical to initiate the immune response and maintain tolerance, depending on different status and subsets. The expression profiles of microRNAs (miRNAs) in various DC subsets and haematopoietic stem cells (HSCs), which generate DCs, remain to be fully identified. Here we examine miRNomes of mouse bone marrow HSCs, immature DCs, mature DCs and IL-10/NO-producing regula...

Journal: :Blood 2014
Christian Thomas Mayer Peyman Ghorbani Amrita Nandan Markus Dudek Catharina Arnold-Schrauf Christina Hesse Luciana Berod Philipp Stüve Franz Puttur Miriam Merad Tim Sparwasser

Multiple subsets of FMS-like tyrosine kinase 3 ligand (FLT3L)-dependent dendritic cells (DCs) control T-cell tolerance and immunity. In mice, Batf3-dependent CD103(+) DCs efficiently enter lymph nodes and cross-present antigens, rendering this conserved DC subset a promising target for tolerance induction or vaccination. However, only limited numbers of CD103(+) DCs can be isolated with current...

Journal: :International journal of oncology 2007
Toshiyasu Ojima Makoto Iwahashi Masaki Nakamura Kenji Matsuda Mikihito Nakamori Kentaro Ueda Teiji Naka Masahiro Katsuda Motoki Miyazawa Hiroki Yamaue

Granulocyte macrophage colony-stimulating factor (GM-CSF) is a key cytokine for the generation and stimulation of dendritic cells (DCs), and it may also play a pivotal role in promoting the survival of DCs. In this study, the feasibility of creating a cancer vaccine using DCs adenovirally transduced with the carcinoembryonic antigen (CEA) gene and the GM-CSF gene was examined. In addition, the ...

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