OBJECTIVE To describe the relationships between dosing strategy, age, and vancomycin trough concentrations in pediatric patients. METHODS This is a retrospective review of hospitalized pediatric patients between 2 months and 17 years of age treated with intravenous vancomycin from 2008 to 2011. The primary outcome was the number of patients achieving a target trough concentration of 10 to 20 ...

A single dose of 200 mg/kg razoxane protected mice against the sub-chronic lethal effects (i.e. within 21 days) of 10 mg/kg daunomycin. When the razoxane dose was split into 2 doses of 100 mg/kg, even better protection against higher doses of daunomycin was obtained. The best protective effect was seen when the razoxane was given 24 h before or simultaneously with the daunomycin, and it was sti...

The study examined the effect of raw and roasted cereals (corn, oat and barley) and soybean in diet on growth performance and blood parameters of lambs fattening. Totally 60 lambs after ablactation at average of 50 days, were tested and equally divided into three groups: an experimental I (E I), experimental II (E II) and a control (C) group. The fattening period lasted 56 days. Lambs of the C ...

The aim of this study was to determine the effect of natural zeolite (commercial preparation with 80% of clinoptilolite) on counts of different physiological groups of bacteria i.e. sulfide-producing, faecal and total coliform, mesophilic aerobic and anaerobic, and thermophilic bacteria in pig slurry. Zeolite was spread daily directly over partially slatted floor in a dose of 0.4 kg/1 m 2 durin...

We reviewed 1233 cases of familial amyloidotic polyneuropathy (FAP) from 489 Portuguese families registered at the Centro de Estudos de Paramiloidose, Porto, Portugal. It was found that in 159 cases, neither parent had shown symptoms of this hereditary dominant form of peripheral neuropathy. These cases appear to form a distinct group, with a later age at onset (mean 45.1 years, SD 12.0) than t...

Effects of hemorrhage on renal nerve activity and of subsequent opiate receptor blockade with naloxone were studied in conscious rabbits. Mean arterial pressure remained constant at 77 +/- 2 mm Hg through 17 +/- 2 ml/kg hemorrhage, while renal nerve activity increased by 159 +/- 16%. After 25 +/- 1 ml/kg hemorrhage, mean arterial pressure fell by 42 +/- 3 mm Hg, and renal nerve activity decreas...

Twenty-three of indigenous Priangan and Javanese Fat-tailed (JFT) ram breeds were used to evaluate its carcass and non carcass components slaughtered at mature live weight. Five Priangan rams and six JFT rams were slaughtered at 32.5 kg of live weight while six other rams of each breeds were also slaughtered at 40 kg of live weight. Before the rams were slaughtered, they were fattened using pel...

Echinacea is used widespread as an herbal paramunity-inducer to reduce various infections in humans. The recommended application is a prophylactic use for several weeks. On the other hand, it was shown that e.g. phagocytosis is depressed by an intake duration exceeding 5 days. The aim of the present trials was to test if a repeated short-time application of Echinacea juice as feed additive is s...