Detection of sequence-specific DNA damage induced by antitumor alkylating agents might provide a mechanism for detecting and discriminating damage specific to one or more of these drugs. Using repetitive primer-extension and human alphoid DNA as a substrate, lesions specific for an activated form of cyclophosphamide, 4-hydroperoxycyclophosphamide, were detected at 32 of 33 guanines within a 200...

Background: Hamstring tendons are secondary hip extensors. Their harvest for graft in anterior cruciate ligament(ACL) reconstruction may create deleterious effect on hip extension strength. This is of particular importance in sportsthat need powerful hip extension force like climbing and sprinting. Due to scarcity of a comprehensive study in thisarea, we designed this prospect...

concrete bridge deck damage detection by measurement and monitoring variables related to vibration signatures is one of the main tasks of any bridge health monitoring system (bhms). generally damage puts some detectable/discoverable signs in the parameters of bridge vibration behavior. however, differences between frequency and mode shape before and after damage are not remarkable as vibration ...

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household food security remains a challenge in south africa. the national government instituted the integrated food security strategy (ifss) programme which identifies household agricultural production as an important element of improving household-level food security. agricultural extension is well positioned to help achieve this aim, but its current contribution is unknown. this study identif...

Many genetic and physiological treatments that extend lifespan also confer resistance to a variety of stressors, suggesting that cytoprotective mechanisms underpin the regulation of longevity. It has not been established, however, whether the induction of cytoprotective pathways is essential for lifespan extension or merely correlated. Using a panel of GFP-fused stress response genes, we identi...

Background: In children with unilateral cerebral palsy (uCP) virtually nothing is known on the relation between structural brain damage and upper limb (UL) kinematics quantified with three-dimensional movement analysis (3DMA). This explorative study aimed to (1) investigate differences in UL kinematics between children with different lesion timings, i.e., periventricular white matter (PWM) vs. ...

Lack of understanding of the extension, education, and development practitioners’ role and their contribution to sustainable agriculture is the main challenge of sustainability projects in Iran. Accordingly, the aim of this study was toidentify the extension system that has been more successful in sustainable horticulture. The population consisted of 22 pioneer farmers that had used or are usin...

The study was carried out to assess the implication of the use of selected Information and Communication Technologies (ICTs) for extension service delivery in Nigeria. The simple random technique was used to select fifty percent of the total extension agents which equivalent to forty-two respondents as sample size for the study. Frequency counts, percentages, mean and standard deviation were us...

AbstractThe purpose of this study was to assess organizational and personnel structure in Iranian Agriculture Extension System (IAES). The research instrument was a structural questionnaire including close-ended questions which its validity and reliability was confirmed by using expert panel and Cranach’s alpha test, respectively. The statistical population of this research included all public ...